Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth +8 more
wiley +1 more source
A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai +5 more
wiley +1 more source
Review of the pseudoscorpion genus Stenohya Beier, 1967 from China (Pseudoscorpiones, Neobisiidae)
Stenohya Beier, 1967 is an Asian pseudoscorpion genus, with more than half of the species reported from China. In this study, eight new Stenohya species from China are described: S. biverticis Zhao, Guo & Zhang sp. nov., S. cordata Zhao, Guo & Zhang sp.
Jiaqi Zhao +3 more
doaj +1 more source
Verbos de desplazamiento en español y en chino: Un análisis subléxico de su significado y sus extensiones semánticas [PDF]
Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Filosofía y Letras, Departamento de Lingüística General, Lenguas Modernas, Lógica y Filosofía de la Ciencia, Teoría de la Literatura y Literatura Comparada. Fecha de lectura:
Luo, Ying
core +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
ВІДОБРАЖЕННЯ ЖІНОЧИХ ПОЗИТИВНИХ ВНУТРІШНІХ ЯКОСТЕЙ В КИТАЙСЬКИХ ТА ПОЛЬСЬКИХ ПРИСЛІВ’ЯХ: ЕТНОЛІНГВІСТИЧНИЙ ПІДХІД [PDF]
The article investigates and compares the positive inner attributes of women reflected in Chinese and Polish proverbs. The sources of the features that underlie the representations of female positive inner attributes from proverbs were found to draw ...
Kharlay, Oksana
core +1 more source
The Tang Dynasty : Quatrains : The boudoir and the frontier : High Tang
Although a small number of Six Dynasties heptasyllabic quatrains are extant, and Early Tang poets experimented with the form, stylistically mature qijue poetry was an invention of the High Tang poets, most notably Wang Changling and Li Bai.
EGAN, Charles
core
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source

