Results 121 to 130 of about 460,215 (289)

UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma

open access: yesCancer Management and Research, 2019
Li-Li Liu,1,2,* Ji-Min Zhu,1,2,* Xiang-Nan Yu,1,2 Hai-Rong Zhu,1,2 Xuan Shi,1,2 Enkhnaran Bilegsaikhan,1,2 Hong-Ying Guo,1,2 Jian Wu,1–3 Xi-Zhong Shen1–3 1Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University ...
Liu LL   +8 more
doaj  

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu   +9 more
wiley   +1 more source

Association of two FOXP3 polymorphisms with breast cancer susceptibility in Chinese Han women

open access: yesCancer Management and Research, 2018
Tian Tian,1,* Meng Wang,1,* Yi Zheng,1,* Tielin Yang,2 Wenge Zhu,3 Hongtao Li,4 Shuai Lin,1 Kang Liu,1 Peng Xu,1 Yujiao Deng,1 Linghui Zhou,1 Zhijun Dai1 1Department of Oncology, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’
Tian T   +11 more
doaj  

Chan–Lam Cross‐Coupling With Alkylboron Reagents: From Transmetallation to Radical Pathways

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Alkylative Chan–Lam coupling overcomes intrinsic transmetallation limitations of alkylboron reagents by engaging radical pathways. Recent advances reveal how radical and radical–polar crossover mechanisms enable mild C(sp3)—heteroatom bond formation. This minireview highlights key mechanistic insights and emerging strategies that transform alkylboron ...
Nicolas G.‐Simonian   +3 more
wiley   +1 more source

Evaluation of Modeling Assumptions for Predicting Structural Damage and Train Derailment Under Earthquake Loading

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT The rapid development of new railway networks and the aging of existing infrastructure in seismic‐prone regions continue to motivate the need for efficient methods to simulate the dynamic behavior of coupled train track structure systems. While detailed train–structure interaction (TSI) models can capture complex mechanisms, they are often too
Miguel A. Gomez, Matthew J. DeJong
wiley   +1 more source

Research on Deformation Prediction of Small Interval Tunnel Based on Machine Learning and Numerical Simulation

open access: yesEnergy Science &Engineering, EarlyView.
This study leverages machine learning algorithms—specifically artificial neural networks (ANN) and genetic programming (GP)—to forecast and analyze variations in vault settlement measurements during excavation of small interval tunnel. A settlement prediction model was developed and validated through comparative analysis with regression to evaluate the
Wenjie Zhai   +7 more
wiley   +1 more source

Long-term icariin treatment ameliorates cognitive deficits via CD4+ T cell-mediated immuno-inflammatory responses in APP/PS1 mice

open access: yesClinical Interventions in Aging, 2019
Tianrui Zhu,1 Feng Zhang,1 Heng Li,1 Yi He,2 Guitao Zhang,1 Nana Huang,1 Mingming Guo,3 Xiaohong Li11Department of Neurology, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong 250013, People’s Republic of China; 2Department ...
Zhu T   +7 more
doaj  

Rheological and Textural Properties of Clean‐Label 3D‐Printed Traditional Thai Dessert

open access: yesFood Bioengineering, EarlyView.
ABSTRACT This study aimed to develop a clean‐label 3D‐printable food ink using a formulation based on Khanom Piak Poon, a traditional Thai dessert, enriched with carrot powder (CP) for enhanced nutritional value. Unlike conventional food printing inks that contain additive hydrocolloids, this ink relies on the natural reactions between starch, sugar ...
Anucha Pramuan   +6 more
wiley   +1 more source

Prognostic value of EGFR and KRAS in resected non-small cell lung cancer: a systematic review and meta-analysis

open access: yesCancer Management and Research, 2018
Shi-Ming Zhang, Qing-Ge Zhu, Xiao-Xiao Ding, Song Lin, Jing Zhao, Lei Guan, Ting Li, Bing He, Hu-Qin Zhang The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi’an JiaoTong ...
Zhang SM   +8 more
doaj  

Strategic construction of fluorinated surroundings in NIR‐II‐emissive organic semiconducting agents for amplifying cancer phototheranostics

open access: yesFlexMat, EarlyView.
The development of conventional phototheranostic nanomedicines suffers from an intrinsic trade‐off between NIR‐II fluorescence emission and phototherapeutic effects, leading to poor overall efficacy. Herein, we propose an innovative fluorination strategy by constructing fluorinated surroundings in NIR‐II‐emissive organic semiconducting agents to ...
Xiaoming Hu   +7 more
wiley   +1 more source

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