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The bioavailability and pharmacokinetics of three zinc salts: Zinc pantothenate, zinc sulfate and zinc orotate

European Journal of Drug Metabolism and Pharmacokinetics, 1982
In this study the authors compared the pharmacokinetics of three zinc salts after parenteral and oral administration to rabbits: zinc sulfate, a soluble mineral salt; zinc pantothenate, a soluble organic salt; and zinc orotate, an insoluble organic salt. The results obtained with the two soluble salts were not significantly different (p less than 0.05).
G, Andermann, M, Dietz
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Zinc tolerance tests in zinc deficient and zinc supplemented diets

The American Journal of Clinical Nutrition, 1986
Seven men consumed a low-zinc (3.3 mg/day) diet for 8 wk, followed by zinc-repletion (+15 mg/day) for 12 days. Zinc tolerance tests (50 mg) were administered initially and following depletion and repletion periods. Plasma zinc after 2 h in the zinc tolerance test was marginally higher after both the depletion (p less than 0.06) and repletion (p less ...
J J, Fickel   +2 more
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Bioavailability of zinc in several sources of zinc oxide, zinc sulfate, and zinc metal.

Journal of Animal Science, 1999
Three zinc depletion-repletion assays were carried out with chicks to determine Zn bioavailability in five sources of ZnO, three sources of ZnSO4.H2O, and two sources of Zn metal. A standard 23% CP corn-soybean meal diet was fed during the first 3 d posthatching, after which it was replaced with a Zn-deficient soy concentrate diet (13.5 mg Zn/kg) until
H M, Edwards, D H, Baker
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Leukocyte Zinc in the Assessment of Zinc Status

CRC Critical Reviews in Clinical Laboratory Sciences, 1984
The problems of assessment of human zinc status are reviewed, with particular emphasis on the limitations to each of the current available measurements. The advantages and limitations of leukocytes are then described. Methods of preparation and potential problems in the assay for zinc are described in detail. The data so-far produced by this method are
J, Patrick, C, Dervish
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Zinc-directed inhibitors for zinc proteinases

Acta Crystallographica Section D Biological Crystallography, 1995
Zinc proteinases have been recognized as a distinct class of proteolytic enzymes in which at least one ion of zinc is involved directly in catalysis. This family includes a growing number of biologically important enzymes which are attractive targets for rational drug design. In this paper we examine the special features of the zinc binding environment
H, Feinberg   +6 more
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The behaviour of zinc and radio-zinc in the rat

Biochimica et Biophysica Acta, 1956
The relationships between protein-bound zinc in the plasma, and zinc in the tissues has been studied in the rat, using radio-zinc. The clearance curve of intravenously administered 65Zn labelled plasma can be divided into four exponential terms, of half-lives 0.74; 6.05; 195; 12, 180 minutes. The last term correlates with the faecal excretion, which
I G, GILBERT, D M, TAYLOR
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Zinc and Zinc Alloys

2001
Abstract This article discusses the composition, properties, and behaviors of zinc and its alloys. It explains where cast and wrought zinc alloys are used, describes commercial designations and grades, and discusses the effect of various alloying elements on properties and performance.
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Zinc-Zinc Chloride

2001
(Zn) [7440-66-6] Zn (MW 65.39) InChI = 1S/Zn InChIKey = HCHKCACWOHOZIP-UHFFFAOYSA-N (ZnCl2) [7646-85-7] Cl2Zn (MW 136.29) InChI = 1S/2ClH.Zn/h2*1H;/q;;+2/p-2 InChIKey = JIAARYAFYJHUJI-UHFFFAOYSA-L (mild reducing agent; causes reductive elimination of vicinal heteroatoms;1-3 reduces activated carbonyls4 and alkenes;5 ...
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Zinc homeostasis and functions of zinc in the brain

Biometals, 2001
The brain barrier system, i.e., the blood-brain and blood-cerebrospinal fluid barriers, is important for zinc homeostasis in the brain. Zinc is supplied to the brain via both barriers. A large portion of zinc serves as zinc metalloproteins in neurons and glial cells.
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Zinc and Zinc Alloys

1998
AbstractThis article provides information on the properties, compositions, designations, and applications of zinc and zinc alloys. It discusses the principal areas of application of zinc: in coatings and anodes for corrosion protection of irons and steels; in zinc casting alloys; as an alloying element in copper, aluminum, magnesium, and other alloys ...
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