Results 41 to 50 of about 1,756,190 (309)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Preoperative oral zinc tablet decreases incidence of postoperative sore throat

open access: yesIndian Journal of Anaesthesia, 2020
Background and Aims: Postoperative sore throat (POST) is very frequently reported after endotracheal intubation. Zinc lozenge has been shown to reduce POST. The aim of this study was to evaluate the effect of dispersible zinc tablet on POST.
Tanmay Sarkar, Tanuka Mandal
doaj   +1 more source

Maternal serum zinc deficiency in cases of neural tube defect in Gorgan, north Islamic Republic of Iran [PDF]

open access: yes, 2009
Previous studies have shown a high rate of neural tube defects (NTD) in Gorgan, northern Islamic Republic of Iran. This case-control study during 2003-04 compared serum zinc levels and other variables in 23 mothers of neonates affected with NTD and 36 ...
Golalipour, M.J.   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Effect of Polyphenols and Zinc Co-Supplementation on the Development of Neoplasms in Rats with Breast Cancer

open access: yesFoods, 2023
The aim of the study was to evaluate the effect of selected polyphenolic compounds: epicatechin, apigenin, and naringenin, administered separately or in combination with zinc (Zn), on the growth and development of the neoplastic process induced by 7,12 ...
Martyna Jastrzębska   +5 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Prevalencia de serología positiva para Helicobacter pylori en trabajadores de una refinería de zinc

open access: yesRevista Médica Herediana, 2004
Objetivo: Determinar la prevalencia de serología positiva para Helicobacter pylori en trabajadores de una refinería de zinc. Material y Métodos: Se incluyeron en el estudio a los trabajadores que acudían para su control pre-vacacional entre los meses de ...
Fernando Francisco Hadad Arrascue   +4 more
doaj  

The interplay of intracellular calcium and zinc ions in response to electric field stimulation in primary rat cortical neurons in vitro

open access: yesFrontiers in Cellular Neuroscience, 2023
Recent pharmacological studies demonstrate a role for zinc (Zn2+) in shaping intracellular calcium (Ca2+) dynamics and vice versa in excitable cells including neurons and cardiomyocytes.
Abdullah J. Alshawaf   +3 more
doaj   +1 more source

A study of zinc resistance and accumulation of zinc in scapania undulata (L) Dum [PDF]

open access: yes, 1976
Scapania undulata (L.) Dum. is a bryophyte which is common in the upland streams of the North East of England. The zinc resistance of S. undulata from zinc enriched and from low zinc sites was investigated by means of laboratory toxicity tests and field ...
Duncker, Marion
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

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