Results 41 to 50 of about 1,516,887 (310)

Zinc Nutrition of Rice Plants as Influenced by Seed Germinated in Zinc Solutions [PDF]

, 1974
In recent years a physiological disorder of rice (Oryza sativa L.) seedlings growing in soils high in exchangeable calcium has been diagnosed as zinc deficiency.
Kasireddy, Narsimaha R., Thompson, Lyell F.   +1 more
core   +2 more sources

A zinc transporter gene required for development of the nervous system. [PDF]

, 2013
The essentiality of zinc for normal brain development is well established. It has been suggested that primary and secondary zinc deficiencies can contribute to the occurrence of numerous human birth defects, including many involving the central nervous ...
Chowanadisai, Winyoo, Graham, David M, Keen, Carl L, Messerli, Mark A, Rucker, Robert B   +4 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Molecular dissection of the domain architecture and catalytic activities of human PrimPol [PDF]

, 2014
PrimPol is a primase–polymerase involved in nuclear and mitochondrial DNA replication in eukaryotic cells. Although PrimPol is predicted to possess an archaeo-eukaryotic primase and a UL52-like zinc finger domain, the role of these domains has not been ...
Aidan J. Doherty, Aravind, Benjamin A. Keen, Bianchi, Biertümpfel, Biswas, Bocquier, Boudsocq, Brautigam, Chen, Chen, Connolly, Corn, Della, Duncan, Engelke, Fogg, Frick, Garcia-Gomez, Graziewicz, Griep, Hays, Iyer, Johnson, Julie Bianchi, Kim, Lao-Sirieix, Lao-Sirieix, Laura J. Bailey, Lehmann, Lipps, Liu, Maga, Masutani, Mendelman, Ohashi, Pelletier, Pinz, Pitcher, Rudd, Shannon, Stanislaw K. Jozwiakowski, Tabor, van Loon, Wan, Washington   +45 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A study of zinc resistance and accumulation of zinc in scapania undulata (L) Dum [PDF]

, 1976
Scapania undulata (L.) Dum. is a bryophyte which is common in the upland streams of the North East of England. The zinc resistance of S. undulata from zinc enriched and from low zinc sites was investigated by means of laboratory toxicity tests and field ...
Duncker, Marion
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Zinc in Wheat Grain, Processing, and Food

Frontiers in Nutrition, 2020
Improving zinc (Zn) content in wheat and its processed foods is an effective way to solve human Zn deficiency, which can cause a variety of diseases. This article summarizes the works on Zn in wheat grain, wheat processing, and wheat-derived foods. Grain
Min Wang, Fanmei Kong, Rui Liu, Qingqi Fan, Xiaocun Zhang, Xiaocun Zhang   +5 more
doaj   +1 more source

Effect of Polyphenols and Zinc Co-Supplementation on the Development of Neoplasms in Rats with Breast Cancer

Foods, 2023
The aim of the study was to evaluate the effect of selected polyphenolic compounds: epicatechin, apigenin, and naringenin, administered separately or in combination with zinc (Zn), on the growth and development of the neoplastic process induced by 7,12 ...
Martyna Jastrzębska, Joanna Giebułtowicz, Andrzej K. Ciechanowicz, Robert Wrzesień, Wojciech Bielecki, Barbara Bobrowska-Korczak   +5 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source