Results 81 to 90 of about 2,160,740 (389)

Revealing the role of crystal orientation of protective layers for stable zinc anode

Nature Communications, 2020
Rechargeable aqueous zinc-ion batteries are a promising candidate for next-generation energy storage devices. However, their practical application is limited by the severe safety issue caused by uncontrollable dendrite growth on zinc anodes.
Qi Zhang, Jingyi Luan, Xiao-bing Huang, Qi Wang, Dan Sun, You-gen Tang, Xiaobo Ji, Hai-yan Wang   +7 more
semanticscholar   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source

Considerations and Challenges for Acute Inhalation Toxicity Testing and Classification of Zinc Sulphide Under REACH

Toxics
Zinc sulphide is a widely used inorganic powder, and its production has reached quantities greater than 1000 t/year. Therefore, in accordance with OECD guideline 436, an acute inhalation test was implemented to provide more accurate data.
Gustav Gerd Bruer, Noömi Lombaert, Arne Burzlaff, Christine Spirlet, Daria Gödecke, Mehmet Ramazanoglu, Otto Creutzenberg   +6 more
doaj   +1 more source

Mutations in Superoxide Dismutase 1 (Sod1) Linked to Familial Amyotrophic Lateral Sclerosis Can Disrupt High-Affinity Zinc-Binding Promoted by the Copper Chaperone for Sod1 (Ccs)

Molecules, 2020
Zinc (II) ions (hereafter simplified as zinc) are important for the structural and functional activity of many proteins. For Cu, Zn superoxide dismutase (Sod1), zinc stabilizes the native structure of each Sod1 monomer, promotes homo-dimerization and ...
Stefanie D. Boyd, Morgan S. Ullrich, Jenifer S. Calvo, Fatemeh Behnia, Gabriele Meloni, Duane D. Winkler   +5 more
doaj   +1 more source

A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang, Da Lin, Dongyuan Liu, Dongxu Zhang, Hao Wang   +4 more
wiley   +1 more source

A Novel Neuroprotective Mechanism of Riluzole: Direct Inhibition of Protein Kinase C

Neurobiology of Disease, 2000
In addition to its antiexcitotoxic action, the anti-amyotrophic lateral sclerosis (ALS) neuroprotectant riluzole protects against nonexcitotoxic oxidative neuronal injury.
Kyung-Min Noh, Jee-Yeon Hwang, Hyung-Cheul Shin, Jae-Young Koh   +3 more
doaj  

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden, Charles Carron, Donatienne Van Weehaeghe, Joke De Vocht, Fouke Ombelet, Pegah Masrori, Caro De Weerdt, Rebecca E. James, Lauren T. Evans, Frederick A. Schroeder, Jacob M. Hooker, Michel Koole, Janice E. Kranz, Tonya M. Gilbert, Philip Van Damme, Koen Van Laere   +15 more
wiley   +1 more source

TrkB mediates BDNF-induced potentiation of neuronal necrosis in cortical culture

Neurobiology of Disease, 2003
In the present study, the signaling mechanisms underlying the effect of brain-derived neurotrophic factor (BDNF) on neuronal necrosis were investigated.
Hyun-Jung Kim, Jung Jin Hwang, M.Margarita Behrens, B.Joy Snider, Dennis W Choi, Jae-Young Koh   +5 more
doaj  

Global research status and intelligent technology development trend of open-pit mining blasting: visualization analysis based on CiteSpace and VOSviewer

Geomechanics and Geophysics for Geo-Energy and Geo-Resources
Blasting is an important process in open-pit mining, and blasting technology directly affects the efficiency, cost and ecology of mine production. Research on blasting in open-pit mining has been progressing, but there is a lack of systematic discussion ...
Jie Tan, Weiming Guan, Anye Cao, Changxin Wang, ZiZhao Zhang, Yun Duan, Hui Chen   +6 more
doaj   +1 more source

Zinc detoxification by a cyanobacterium from a metal contaminated bay in Brazil

Brazilian Archives of Biology and Technology, 2004
We describe here the trapping of zinc in polyphosphate granules of the cyanobacterium Synechocystis aquatilis NPBS-3. Cells were cultured in 25 µM of zinc chloride and prepared for electron microscopy and energy-dispersive X-ray analysis.
Luciana Andrade, Carolina N. Keim, Marcos Farina, Wolfgang C. Pfeiffer   +3 more
doaj   +1 more source