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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Background: Zinc deficiency is one of the major public health problems especially in developing countries, with an estimation of over 80% of pregnant women to be zinc deficient worldwide.
Man Kumar Tamang +3 more
doaj +1 more source
A second‐born breastfed infant presented with zinc deficiency. His mother had a novel heterozygous mutation in SLC30A2. A previous baby did not have zinc deficiency but the mother had taken a proton pump inhibitor (PPI) during the second pregnancy ...
Emma Porter +3 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Study the Therapeutic Role of Zinc and Vitamin D3 in Juvenile Male Rats with Zinc Deficiency; Hormonally and Histologically [PDF]
The current experience was carried out to evaluated the impacts of Zinc and VitD3 on the thyroid gland, and testicular functions as well as bone tissue architecture in rats with zinc deficiency, forty juvenile rats were used, and Zinc ...
Maryam ALmously
doaj +1 more source
BackgroundZinc is an essential mineral known to be important for the normal physiological functions of the immune system. It is one of the basic nutrients required during pregnancy for the normal development and growth of the fetus.
Eskeziaw Agedew +8 more
doaj +1 more source
Zinc deficiency in patients with chronic pancreatitis
BACKGROUND Zinc is a key element in numerous proteins and plays an important role in essential cell functions such as defense against free radicals and DNA damage repair.
M. Vujasinovic +6 more
semanticscholar +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Background Zinc deficiency can change the concentrations of minerals and trace elements in the body. However, previous studies still had many limitations. Objective To reveal the effects of zinc deficiency on homeostasis of 16 minerals and trace elements.
Qingli Yu +9 more
doaj +1 more source

