Results 71 to 80 of about 1,676,860 (295)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A Systematic Review and Meta-analysis on the Prevalence of Zinc Deficiency in Iranian Population [PDF]

open access: yesJournal of Pediatrics Review, 2023
Objectives: This study aims to assess the zinc deficiency prevalence in Iran during the past two decades and compare it with other countries. Methods: We searched PubMed, Google Scholar, Web of Sciences, Scientific Information Database (SID), and Magiran
Mohammad Javad Eslami   +2 more
doaj  

Zinc deficiency primes the lung for ventilator-induced injury.

open access: yesJCI Insight, 2017
Mechanical ventilation is necessary to support patients with acute lung injury, but also exacerbates injury through mechanical stress-activated signaling pathways.
F. Boudreault   +14 more
semanticscholar   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Zinc Deficiency in First Year Female Students of Tehran University of Medical Sciences

open access: yesJournal of Family and Reproductive Health, 2008
Objective: Zinc deficiency is an important health problem in developing countries. The aim of this study was diagnosis of zinc deficiency among young female students of Tehran University of Medical Sciences.
Fedyeh Haghollahi   +9 more
doaj  

The prevalence of zinc deficiency in 6-month to 12-year old children in Bandar Abbas in 2013

open access: yesElectronic Physician, 2017
Background: Zinc deficiency is an important problem in children, especially in developing countries. Zinc supplements have beneficial effects on multiple factors, including treatment of growth retardation and hypogonadism, and they can be used as ...
Mohammadbagher Rahmati   +3 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Infants and elderlies are susceptible to zinc deficiency

open access: yesScientific Reports, 2016
The importance of zinc for human health has been recognized since the early 1960s, but today there is little concern about zinc deficiency in developed countries. In this study, we measured the zinc concentration in hair from 28,424 Japanese subjects (18,
H. Yasuda, Toyoharu Tsutsui
semanticscholar   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

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