Differential expression of synaptophysin and synaptoporin during pre- and postnatal development of the hippocampal network [PDF]
The closely related synaptic vesicle membrane proteins synaptophysin and synaptoporin are abundant in the hippocampal formation of the adult rat. But the prenatal hippocampal formation contains only synaptophysin, which is first detected at embryonic day
Amaral +51 more
core +1 more source
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
An overview of progress in electrolytes for secondary zinc-air batteries and other storage systems based on zinc [PDF]
The revived interest and research on the development of novel energy storage systems with exceptional inherent safety, environmentally benign and low cost for integration in large scale electricity grid and electric vehicles is now driven by the global
Abbott +393 more
core +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Improved, low cost inorganic-organic separators for rechargeable silver-zinc batteries [PDF]
Several flexible, low-cost inorganic-organic separators with performance characteristics and cycle life equal to, or better than, the Lewis Research Center Astropower separator were developed.
Sheibley, D. W.
core +1 more source
Lithiophilic Current Collector Without Interfacial Penalty in Zero‐Excess Lithium Metal Batteries
Bilayer lithiophilic coatings are introduced to overcome the structural fragility of conventional single‐layer current collectors in zero‐excess Li‐metal batteries (ZE‐LMBs). By integrating density functional theory with electrochemical analyses, the Ag‐outer/Pt‐inner configuration enables uniform Li deposition, robust SEI formation, and persistent ...
Jiyeon Seo +8 more
wiley +1 more source
Cross-linked polyvinyl alcohol films as alkaline battery separators [PDF]
Cross-linking methods were investigated to determine their effect on the performance of polyvinyl alcohol (PVA) films as alkaline battery separators. The following types of cross-linked PVA films are discussed: (1) PVA-dialdehyde blends post-treated with
Gonzalez-Sanabria, O. D. +2 more
core +1 more source
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul +12 more
wiley +1 more source
Fundamental Studies Connected with Electrochemical Energy Storage [PDF]
Papers are presented which deal with electrochemical research activities. Emphasis is placed on electrochemical energy storage devices. Topics discussed include: adsorption of dendrite inhibitors on zinc; proton discharge process; electron and protron ...
Buck, E., Sen, R.
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source

