Results 161 to 170 of about 16,726 (302)

Biomimetic Iridium‐Based Photothermal Nanozyme to Trigger Ferroptosis and Pyroptosis and Activate the cGAS‐STING Pathway for Improved Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops an iridium‐based nanozyme (IIN@M) with superior enzyme‐like activity and photothermal performance. It disrupts intracellular redox balance by generating reactive oxygen species and depleting glutathione, which synergistically induces ferroptosis, pyroptosis, and immunogenic cell death.
Lijun Ding, Zhongxiong Fan, Guoyu Xia, Fukai Zhu, Nan Yang, Shujie Yu, Longlong Yuan, Jinyao Li   +7 more
wiley   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Laterally Oriented Dendritic Passivation via In Situ Zn Reconstruction for Stabilizing NiMo Catalysts under Dynamic Electrolysis

Advanced Science, EarlyView.
This study highlights the effectiveness of Zn‐induced dendrite layers in enhancing the durability of NiMo HER catalysts under dynamic electrochemical conditions. Through in situ dendritic passivation, the Zn‐NiMo catalyst preserves catalytic active sites and mitigates irreversible Ni oxidation/hydroxylation during repeated load fluctuation.
Taeyoung Jeong, Hyun‐Jae Park, Myeongjin Kim   +2 more
wiley   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Electrode Engineering for High‐Durability Variable‐Emissivity Devices Based on Reversible Copper Electrodeposition

Advanced Science, EarlyView.
An Ir‐based reversible copper electrodeposition variable‐emissivity device achieved over 8000 cycles with just 11% radiative temperature variation decay. This stability stems from Ir's inherent inertness, high conductivity, and strength, which collectively suppress cracking and corrosion.
Runyun He, Tianwen Liu, Liqiang Zhang, Tuoyu Liu, Dan Tang, Wenxia Zhang, Jundong Tao, Tingting Shi, Yijing Song, Haifeng Cheng, Yao Zhang, Dongqing Liu   +11 more
wiley   +1 more source

Inorganic Interface Engineering for Stabilizing Zn Metal Anode. [PDF]

Nanomicro Lett
Yuan S, Zhao W, Song Z, Lin H, Zhao X, Feng Z, Xu ZJ, Fan H, Zou Q.   +8 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Rational Electrolyte Structure Engineering for Highly Reversible Zinc Metal Anode in Aqueous Batteries. [PDF]

Nanomicro Lett
Zhuang Y, Liang Y, Zhang W, Sun Y, Wang Z, Guan J, Zhu B, Cui J, Tang J, Lee JM, Zhu J.   +10 more
europepmc   +1 more source

Adhesive Tape‐Inspired Polymer Coatings Enable Record‐Stable Zinc Anodes for High‐Rate Aqueous Batteries

Advanced Science, EarlyView.
An adhesive tape–inspired anode stabilization strategy is proposed by grafting poly(methyl methacrylate) onto natural rubber. The resulting copolymer coating exhibits elasticity, adhesion, and ion‐selective nanodomains, which lower Zn2+ desolvation barriers, guide deposition to the stable (002) facet, and ensure intimate interfacial contact, delivering
Shuo Zhao, Shuyue Luo, Yangming Zhang, Rongyan Xie, Zhen Liu, Zhengyin Yao, Xianru He, Jiangbo Li, Xiang Yao, Zhou Zhou, Dongbai Sun, Peng Zhang   +11 more
wiley   +1 more source

In-Operando X-Ray Imaging for Sobering Examination of Aqueous Zinc Metal Batteries. [PDF]

Nanomicro Lett
Dai Y, He H, Ouyang M, Chen J, Lin J, Dong H, He G.   +6 more
europepmc   +1 more source