Results 41 to 50 of about 1,022,147 (306)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Global research status and intelligent technology development trend of open-pit mining blasting: visualization analysis based on CiteSpace and VOSviewer

Geomechanics and Geophysics for Geo-Energy and Geo-Resources
Blasting is an important process in open-pit mining, and blasting technology directly affects the efficiency, cost and ecology of mine production. Research on blasting in open-pit mining has been progressing, but there is a lack of systematic discussion ...
Jie Tan, Weiming Guan, Anye Cao, Changxin Wang, ZiZhao Zhang, Yun Duan, Hui Chen   +6 more
doaj   +1 more source

The transfer of heavy metals through trophic levels and their toxicity effects on organisms including humans [PDF]

, 2007
This research has investigated a number of topics pertaining to the effects of metalliferous mining. The combination of these has shown that past mining activities and their resultant waste have led to the accumulation of metals through trophic levels ...
Mitchell, K, Mitchell, Kirsty
core  

Entropy‐Driven Design of Low‐Melting‐Point Alloys via Compositionally Complex Strategy

Advanced Engineering Materials, EarlyView.
Conventional low‐melting‐point alloys (LMPAs) are limited by a narrow compositional space and inherent property trade‐offs. This review presents an entropy‐driven design strategy that overcomes these limitations, ushering in a new class of low‐melting‐point compositionally complex alloys (LMCCAs).
Yinghui Shang, Jianxiang Zhao, Zhaoqi Chen, Hao Gong, Yinsen Yan, Junlei Tao, Yong Yang   +6 more
wiley   +1 more source

Multi-Source Sensing and Interpretable Ensemble Learning for Cross-Validated Performance-Weighted Evaluation of Open-Pit Blasting Performance

Applied Sciences
Comprehensive evaluation of open-pit blasting is challenging because performance indicators originate from different sensing sources and are predicted with different levels of model performance.
Hui Chen, Xinghang Zhang, Zhiyuan Qi, Fei Gao, Jianling Wan, Hongyan Xu, Haiyue Yu, Chengyuan Guan, Yin Chen   +8 more
doaj   +1 more source

Mining proteomes for zinc finger persulfidation

RSC Chemical Biology
A meta-analysis of 22 persulfide-specific proteomics datasets reveals widespread persulfidation of zinc finger proteins across various species, highlighting the role of persulfidation as an important post-translational modification.
Haoju Li, Andrew T. Stoltzfus, Sarah L. J. Michel   +2 more
openaire   +2 more sources

Self‐Sintering Ionogel Binder for Flexible, Recyclable, and Healable Printed Giant Magnetoresistive Sensors

Advanced Functional Materials, EarlyView.
ABSTRACT Electronic waste has emerged as a major environmental challenge, driven by the massive consumption and a limited lifetime of modern electronic devices, stimulating the development of sustainable electronics. Here, an all‐biomaterial gelatin‐choline‐citric acid ([Ch][CA]) ionogel is developed as an active binder to realize self‐sintered ...
Lin Guo, Xiaotao Wang, Guannan Mu, Proloy Taran Das, Igor Veremchuk, Conrad Schubert, Aaron D. Cross, Yevhen Zabila, Xuan Peng, Larysa Baraban, Denys Makarov   +10 more
wiley   +1 more source

Three local plants adapt to ecological restoration of abandoned lead-zinc mines through assembly of rhizosphere bacterial communities

Frontiers in Microbiology
IntroductionThe plant restoration and ecological restoration of lead-zinc mines are very important.MethodsIn this study, we used three local plants to carry out ecological restoration of abandoned lead–zinc mining areas and detected the adaptive ...
Wei Gao, Shuyi Chen, Xin Yu, Sumin Chen, Caijing Wan, Ying Wang, Peng Wu, Qiang Li   +7 more
doaj   +1 more source

Towards Using MMO Anodes in Zinc Electrorefining: Mn Removal by Simulated Plant Off-Gas

Metals, 2023
Implementing mixed metal oxide (MMO) anodes in zinc electrowinning is highly desired due to the considerable reduction in electrical energy consumption. However, the presence of manganese in the electrolyte is a major obstacle for implementing MMO anodes
Masoomeh Askarian, Fariba Mousavi, Roozbeh Mollaabbasi, Elyse Benguerel, Carl Brown, Georges Houlachi, Houshang Alamdari   +6 more
doaj   +1 more source

Zinc Gluconate in the Treatment of Dysgeusia—a Randomized Clinical Trial [PDF]

, 2005
In the treatment of dysgeusia, the use of zinc has been frequently tried, with equivocal results. The aim of the present randomized clinical trial, which involved a sufficiently large sample, was therefore to determine the efficacy of zinc treatment ...
Heckmann, J.G., Wichmann, M., Heckmann, S.M., Hujoel, P., Hummel, T., Habiger, S., Friess, Wolfgang   +6 more
core   +1 more source