Results 171 to 180 of about 25,010 (253)

Translation and Cross‐Cultural Adaptation of the Chronic Rhinosinusitis Control Test for Global Use

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction The Chronic Rhinosinusitis Control Test (CRCT) is a patient‐reported outcome measure (PROM) written in English that is psychometrically validated to measure chronic rhinosinusitis control. Because the availability of translated PROMs is a driver of data equity—collection of data that is fair and generally representative—our ...
Hye K. Pae   +52 more
wiley   +1 more source

Biomonitoring of urban ultrafine particle exposure and associated health effects. [PDF]

open access: yesInt J Public Health
Fireman EM   +3 more
europepmc   +1 more source

Inflammatory Signatures Beyond Th1/Th2 Endotypes Provide Insights Into Postoperative Recurrence in Chronic Rhinosinusitis

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) represents a spectrum of inflammatory endotypes, driven by distinct T helper (Th) immune responses. The high rate of recurrent disease despite appropriate medical and surgical interventions highlights the need for improved characterization beyond the traditional type 2 and non‐type 2 phenotypes to better
Liyona Kampel   +9 more
wiley   +1 more source

Toward Cell‐Specific Molecular MRI: Modulating Chemical Exchange Saturation Transfer Contrast With Manganese

open access: yesAngewandte Chemie, EarlyView.
Manganese‐modulated chemical exchange saturation transfer (CEST) MRI, Manga CEST, leverages intracellular Mn2+ uptake to selectively perturb CEST contrast. Comparing Z‐spectra before and after Mn reveals compartment‐specific contributions. In vivo, neuron‐enriched Mn accumulation induces frequency‐dependent attenuation (3–4 ppm), enabling cell‐weighted
Eleonora Cavallari   +3 more
wiley   +2 more sources

Barriers to Care for Obstructive Sleep Apnea: Primary Care Perspectives at a Safety Net Hospital. [PDF]

open access: yesLaryngoscope Investig Otolaryngol
Florentine M   +4 more
europepmc   +1 more source

Irreversible Electroporation for Inferior Turbinate Reduction Ablation in Adults

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Inferior turbinate hypertrophy is a common cause of nasal airway obstruction. An optimal surgical approach should provide effective volume reduction while preserving mucosal integrity and minimizing postoperative morbidity. Objective To evaluate the safety and efficacy of irreversible electroporation (IRE) for non‐thermal ablation ...
Narin Nard Carmel Neiderman   +9 more
wiley   +1 more source

Ligand‐Directed Molecular Beacons as Turn‐On Fluorescent Probes for Sensing Cell‐Surface Receptor‐Ligand Interactions

open access: yesAngewandte Chemie, EarlyView.
Multivalent, ligand‐directed molecular beacons enable fluorescence turn‐on detection of cell‐surface receptors in living cells. The probes strongly engage closely spaced membrane receptors and exhibit conformation‐dependent fluorescence enhancement at the cell surface, enabling wash‐free receptor imaging, inhibitor screening, and functional evaluation ...
Noa Oppenheimer‐Low   +11 more
wiley   +2 more sources

Developing a strain‐dependent susceptibility to hepatocellular carcinoma in a murine model based on histopathological evidence and genetic context

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Using F1 (C57BL/6J/Smad4+/− X CC) mice, we found that partial loss of Smad4 promotes liver carcinogenesis in a strain‐dependent manner, highlighting the importance of genetic modifiers in tumor susceptibility. The use of Collaborative Cross mice provides a valuable platform for uncovering genotype‐specific cancer susceptibilities in preclinical ...
Osayd Zohud   +3 more
wiley   +1 more source

Blood SOD1 Activity in ALS Patients Receiving Tofersen Treatment

open access: yesAnnals of Neurology, EarlyView.
Objective The antisense oligonucleotide tofersen is the first disease‐modifying drug for SOD1‐related amyotrophic lateral sclerosis (ALS) and was approved because of its ability to reduce SOD1 protein and neurofilament levels. The effect of tofersen on SOD1 activity is unclear but of clinical relevance because homozygous SOD1 mutations, linked to ...
Katharina Goehring   +18 more
wiley   +1 more source

Engineering Atomically Precise Cu4I4 Nanoclusters With Integrated Adsorption and Hydrogenation Functions for Efficient Photocatalytic Nitrate‐to‐Ammonia Conversion

open access: yesAngewandte Chemie, EarlyView.
Efficient photocatalytic nitrate‐to‐ammonia conversion is achieved over an atomically precise Cu4I4 motif through dual‐site cooperation. Lewis‐acidic Cu centers promote nitrate adsorption and activation, while adjacent I sites facilitate active hydrogen generation for stepwise hydrogenation.
Wanting Zhang   +13 more
wiley   +2 more sources

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