Results 31 to 40 of about 116,541 (296)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Mnemotope of Zion and Theopolitical Chronotopes in Ottoman Macedonia

Colloquia Humanistica, 2020
Mnemotope of Zion and Theopolitical Chronotopes in Ottoman Macedonia The discussion in the text, through the intersection of the disciplines of literature and history, oral poetry and ethical sermons from the period of the Enlightenment process in ...
Sofija Grandakovska
doaj   +1 more source

Response Rate of the Third and Fourth Doses of the BNT162b2 Vaccine Administered to Cancer Patients Undergoing Active Anti-Neoplastic Treatments

Diseases, 2023
The BNT162b2 vaccine is globally used for preventing morbidity and mortality related to COVID-19. Cancer patients have had priority for receiving the vaccine due to their diminished immunity.
Abed Agbarya, Ina Sarel, Tomer Ziv-Baran, Orna Schwartz, Yelena Shechtman, Ella Kozlener, Rasha Khoury, Mohammad Sheikh-Ahmad, Leonard Saiegh, Forat Swaid, Asala Abu Ahmad, Urska Janzic, Ronen Brenner   +12 more
doaj   +1 more source

Worship: the source and summit of faith [PDF]

, 1983
In worship God comes to serve his people with his gifts. Worship, as God\u27s service of us, is the source of faith. Worship is also the summit of faith as God lifts his people to himself, to the service of others, to a reconciliation with the natural ...
Pfatteicher, Philip H.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Disease Ecology of a Low-Virulence Mycoplasma ovipneumoniae Strain in a Free-Ranging Desert Bighorn Sheep Population

Animals, 2022
Infectious pneumonia associated with the bacterial pathogen Mycoplasma ovipneumoniae is an impediment to bighorn sheep (Ovis canadensis) population recovery throughout western North America, yet the full range of M.
Brianna M. Johnson, Janice Stroud-Settles, Annette Roug, Kezia Manlove   +3 more
doaj   +1 more source

Non-monotonicity of the frictional bimaterial effect

, 2017
Sliding along frictional interfaces separating dissimilar elastic materials is qualitatively different from sliding along interfaces separating identical materials due to the existence of an elastodynamic coupling between interfacial slip and normal ...
Achenbach, Achenbach, Adams, Aldam, Allam, Ampuero, Andrews, Bar-Sinai, Baumberger, Ben-Zion, Ben-Zion, Ben-Zion, Ben-Zion, Ben-Zion, Ben-Zion, Ben-Zion, Ben-Zion, Ben-Zion, Bhat, Bohnhoff, Brener, Brietzke, Calderoni, Cochard, Crupi, Dade, DeDontney, Dor, Dor, Dowson, Dunham, Eberhart-Phillips, Erickson, Gabuchian, Geubelle, Harris, Huang, Landau, Langer, Lay, Legros, Lengliné, Lenglinė, Lewis, Lewis, Lipovsky, Lotto, Lyakhovsky, Lykotrafitis, Marone, Mitchell, Oglesby, Ozakin, Persson, Prakash, Prakash, Prakash, Ranjith, Rice, Rice, Rice, Rockwell, Ross, Rubin, Rubin, Rubin, Ruina, Sandvol, Satake, Scala, Scholz, Scholz, Share, Shi, Shlomai, Thomas, Turcotte, Uenishi, Wang, Weertman, Weertman, Wiens, Winberry, Xia, Xu, Xu, Xu, Yamashita, Yang, Zaliapin, Şengör   +90 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Redemption, settlement and agriculture in the religious teachings of Hovevei Zion

HTS Teologiese Studies/Theological Studies, 2021
Hovevei Zion is a collective name for several societies established in Eastern Europe in the 19th century, advocating immigration to the land of Israel, settlement of the land and agricultural work. This article examines the religious approach of several
Amir Mashiach
doaj   +1 more source

Journal of African Christian Biography: v. 3, no. 2 [PDF]

, 2018
A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: 1.
Bonk, Jonathan, Chimininge, Vengesai, Daneel, Marthinus Louis, Robert, Dana L.   +3 more
core