Results 1 to 10 of about 12,603 (200)

Efficacy of Different Combination Therapies for Mania in Bipolar Disorder: A Systematic Review and Meta‐Analysis [PDF]

open access: yesBrain and Behavior
Objective To systematically evaluate the efficacy and safety of different combination therapies in the treatment of mania in bipolar disorder, and to provide evidence‐based support for individualized clinical treatment.
Peiling Yao, Pingan Ni, Liqin Yin
doaj   +3 more sources

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness [PDF]

open access: yesNew England Journal of Medicine, 2018
BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute ...
Timothy D Girard   +2 more
exaly   +3 more sources

Comparison of ziprasidone and olanzapine on cognitive function in patients with schizophrenia at different stages: a prospective study in Huai’an, China [PDF]

open access: yesFrontiers in Behavioral Neuroscience
ObjectiveTo compare the effects of ziprasidone and olanzapine on cognitive function in patients with first-episode schizophrenia and chronic schizophrenia at different stages.MethodsCognitive function tests were performed on chronic schizophrenic ...
Jingjing Yao   +7 more
doaj   +2 more sources

Impact of CYP3A4 functional variability on ziprasidone metabolism [PDF]

open access: yesFrontiers in Pharmacology
IntroductionZiprasidone is primarily metabolized by CYP3A4, an enzyme with genetic variability and susceptibility to inhibition or induction. This study explored the functional variability of CYP3A4 in ziprasidone metabolism, focusing on drug ...
Qi Zhou   +8 more
doaj   +2 more sources

Reclaiming Pharmacovigilance: Bridging the Evidence-Practice Gap in Psychopharmacology. [PDF]

open access: yesJ Eval Clin Pract
Journal of Evaluation in Clinical Practice, Volume 32, Issue 2, March 2026.
De Las Cuevas C.
europepmc   +2 more sources

Efficacy and Tolerance of Antipsychotics Used for the Treatment of Patients Newly Diagnosed with Schizophrenia: A Systematic Review and Meta-Analysis

open access: yesPharmacy, 2023
This systematic review compared the efficacy and tolerance of oral antipsychotics (APDs) used in the treatment of schizophrenia following the PRISMA-P© statement (n = 21).
Zina Sherzad Qadir   +2 more
doaj   +1 more source

Ziprasidone Induces Rabbit Atrium Arrhythmogenesis via Modification of Oxidative Stress and Sodium/Calcium Homeostasis

open access: yesBiomedicines, 2022
Background: Atypical antipsychotics increase the risk of atrial arrhythmias and sudden cardiac death. This study investigated whether ziprasidone, a second-generation antipsychotic, affected intracellular Ca2+ and Na+ regulation and oxidative stress ...
Buh-Yuan Tai   +4 more
doaj   +1 more source

Efficacy and Tolerability of Ziprasidone Use in Children and Adolescents, a Systemic Review and Meta Analysis

open access: yesEuropean Psychiatry, 2022
Introduction Ziprasidone is an atypical antipsychotic that has demonstrated efficacy for the treatment of bipolar disorder and schizophrenia. There is some preliminary evidence for Ziprasidone use in children and adolescents with several open label ...
A. Wadhwa   +3 more
doaj   +1 more source

Tolerability of Ziprasidone Use in Children and Adolescents: A Prisma Model: Systematic Review and Meta-Analysis

open access: yesEuropean Psychiatry, 2022
Introduction Studies have demonstrated that Ziprasidone use may be beneficial in children. Determining its potential risks and benefits when used in children is therefore important.
J. Jay   +7 more
doaj   +1 more source

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