Results 151 to 160 of about 29,267 (265)

The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, restores blood–brain barrier integrity in a human stem cell‐based model of ischaemic stroke

open access: yesBritish Journal of Pharmacology, EarlyView.
Ischaemic stroke is characterised by acute cerebrovascular occlusion and blood–brain barrier (BBB) breakdown. Our results indicated that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) ameliorated the loss of BBB integrity, changed the morphology of brain endothelial cells, increased the level of basement membrane and ...
Anikó Szecskó   +14 more
wiley   +1 more source

Ten‐Year Post‐Loading Outcomes of Subcrestally Placed Implants With Internal Conical Connections at 0.5 mm Versus 1.5 mm Depth: A Multicentre Within‐Person Randomised Controlled Trial

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate whether placing single dental implants either 0.5 or 1.5 mm subcrestally in healed bone crests confers any clinical benefits. Materials and Methods Sixty partially edentulous patients requiring two single implant‐supported crowns were enrolled in a split‐mouth design across six centres. Each site was randomly assigned to
Marco Esposito   +9 more
wiley   +1 more source

A Randomised Controlled Trial Comparing a One‐Piece Zirconia Tissue‐Level Implant and Two‐Piece Titanium Bone‐Level Implant for Maxillary Single Tooth Replacement—3 year Results

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This RCT evaluated and compared the clinical performance of zirconia and titanium dental implants placed in the maxillary premolar region. Outcomes were assessed 3 years after prosthetic loading and included marginal bone level (MBL) changes, clinical parameters, aesthetic outcomes, and patient related outcome measures (PROMs ...
J. H. W. de Beus   +8 more
wiley   +1 more source

Effect of Implant Design on Fracture Resistance, Mode, and Crystal Structure of One‐ and Two‐Piece Zirconia Implants With Ceramic or Titanium Abutment Screws: An In Vitro Study

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate the fracture resistance, fracture modes, and crystalline phase changes of zirconia one‐piece implants (OPI) and bone‐level (BLTPI) or tissue‐level, two‐piece implants (TLTPI), with ceramic (C) or titanium (T) abutment screws after dynamic preloading in a moist environment.
Abdulaziz Gul   +5 more
wiley   +1 more source

Block Versus Particulate Deproteinized Bovine Bone Mineral for Guided Bone Regeneration of Peri‐Implant Dehiscence Defects: A 5‐Year Randomized Controlled Trial

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT To assess the 5‐year dimensional stability of buccal hard‐tissues following guided bone regeneration (GBR) of peri‐implant dehiscence defects using deproteinized bovine bone mineral (DBBM) blocks or particulate. Methods Patients requiring single‐tooth implants and presenting a buccal dehiscence defect (≥ 3 mm) at implant placement were ...
Anina N. Zuercher   +5 more
wiley   +1 more source

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