Results 71 to 80 of about 34,222 (305)
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
InP/ZnS Nanocrystals as Fluorescent Probes for the Detection of ATP
, 2014 This article reports on a study on fluorescence adenosine triphosphate (ATP) detection by InP/ZnS quantum dots (QDs). We present a spectroscopic analysis displaying the effect of enzymatic reactions of glucose oxidase (GOX) and hexokinase (HEX) on the ...
Salam Massadeh +5 more
core +1 more source
ACS Applied Materials & Interfaces, 2014 Environmentally friendly nanocrystals (NCs) such as InP are in demand for various applications, such as biomedical labeling, solar cells, sensors, and light-emitting diodes (LEDs). To fulfill their potential applications, the synthesis of such high-quality "green" InP NCs required further improvement so as to achieve better stability, higher brightness
Lifei Xi +8 more
openaire +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Planar Functions from Zn to Zn
Journal of Algebra, 2000 AbstractIn this paper, we show that there are no planar functions from Z3pq to Z3pq where p and q are distinct primes larger than 3. As a result, there are only two undecided cases for planar functions from Zn to Zn if n is not a prime and n≤50,000.
Leung, Ka Hin, Ma, Siu Lun, Tan, Victor
openaire +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
, 2021 Multiphase metal sulfides have proven to show better lithium storage performance than their single phase competitors. However, rational designing of multiphase metal sulfides with rich phase boundaries and heterointerfacial structures is still a big ...
Ma, Yinglan +7 more
core +1 more source
Proceedings of the International Conference on Applied Innovations in ITNanostructured thin films of Iron (Fe)-doped Zinc Sulfide (ZnS) were deposit via Chemical Spray Pyrolysis (CSP) technique, with varying concentrations of Iron incorporated into the ZnS matrix.
Zainab Al-Ramadhan +6 more
doaj +1 more source
STUDY OF PHOSPHORS ZnS:Mn,Cl PHOTOLUMINESCENCE UNDER DYNAMICAL PHOTOEXCITATION
Вестник Северо-Кавказского федерального университета, 2022 Photoluminescence excitation of ZnS:Mn,Cl with different activator concentration was study using static and dynamical photoexcitation regimes. We determined that concentration of manganese and regime of photoexcitation has a great influence on form of ...
Leonid Mikhnev +7 more
doaj