Results 111 to 120 of about 235 (141)
Some of the next articles are maybe not open access.
Journal of Heterocyclic Chemistry, 2020
AbstractA green and efficient mechanochemical method for the synthesis of a series of 2‐arylimidazo[1,2‐a]pyridines was developed using an electrical grinder. I2 catalyzed mechanochemical grinding facilitates the cyclocondensation reaction between various aryl methyl ketones and 2‐aminopyridines to afford 2‐arylimidazo[1,2‐a]pyridines in good yields at
Dharmendra Das +4 more
openaire +1 more source
AbstractA green and efficient mechanochemical method for the synthesis of a series of 2‐arylimidazo[1,2‐a]pyridines was developed using an electrical grinder. I2 catalyzed mechanochemical grinding facilitates the cyclocondensation reaction between various aryl methyl ketones and 2‐aminopyridines to afford 2‐arylimidazo[1,2‐a]pyridines in good yields at
Dharmendra Das +4 more
openaire +1 more source
[The pharmacokinetics of 14C-zolimidine in rats].
Arzneimittel-Forschung, 1976The blood levels and urinary and fecal excretion of 14C-zolimidine [2-(p-methylsulfonyl)-imidazo(1,2-a)pyridine-2-14Ci1 were studied following oral and intravenous application. The elimination from the blood after i.v. administration can be described by a 3-compartment model. Male rats eliminate the radioactivity more rapidly than do females.
E, Schraven, D, Trottnow
openaire +1 more source
The effect of zolimidine, imidazopyridine-derivate, on the duodenal ulcer healing.
Scandinavian journal of gastroenterology. Supplement, 1980Zolimidine, a derivate of imidazopyridine, has a gastroprotective effect. Encouraged by the good results with zolimidine therapy in the literature we initiated a clinical study of zolimidine in duodenal ulcer healing.
D, Belohlavek, P, Malfertheiner
openaire +1 more source
Bollettino della Societa italiana di biologia sperimentale, 1981
A reversal phase partition chromatographic system analysis cimetidine and zolimidine in pharmaceutical dosage forms is proposed. The rapidity and sensitivity of the method could find an useful application in problems of clinical interest.
M I, La Rotonda +2 more
openaire +1 more source
A reversal phase partition chromatographic system analysis cimetidine and zolimidine in pharmaceutical dosage forms is proposed. The rapidity and sensitivity of the method could find an useful application in problems of clinical interest.
M I, La Rotonda +2 more
openaire +1 more source
Arzneimittel-Forschung, 1976
The relative distribution of radioactivity after i.v. (5 mg/kg) and oral (25 mg/kg) application of 14C-Zolimidine [2-(p-methyl-sulfonylphenyl)-imidazo-(1,2-a)-pyridine-2-14C] was examined in male rats by whole-body autoradiography and scintillation fluid spectrometry. 14C-Activity was remarkably concentrated in the stomach of i.v.
J, Ostrowski, E, Schraven, M, Keil
openaire +1 more source
The relative distribution of radioactivity after i.v. (5 mg/kg) and oral (25 mg/kg) application of 14C-Zolimidine [2-(p-methyl-sulfonylphenyl)-imidazo-(1,2-a)-pyridine-2-14C] was examined in male rats by whole-body autoradiography and scintillation fluid spectrometry. 14C-Activity was remarkably concentrated in the stomach of i.v.
J, Ostrowski, E, Schraven, M, Keil
openaire +1 more source
Recent trends in the synthesis of ‘Zolimidine’: a mini-review
Chemical Papers, 2023Parteek Prasher, Mousmee Sharma
openaire +1 more source
Scandinavian journal of gastroenterology. Supplement, 1984
We have studied gastric mucus secretion after carbenoxolone, zolimidine and prostanoic acid short term treatment (28 days) in patients with endoscopically demonstrated peptic gastric ulcer of the lesser curvature. Six patients were treated with carbenoxolone (300 mg/day), 6 with zolimidine (1200 mg/day) and 6 with prostanoic acid (2 g/day). All of them
M C, Parodi, F, Molinari, S, Barocci
openaire +1 more source
We have studied gastric mucus secretion after carbenoxolone, zolimidine and prostanoic acid short term treatment (28 days) in patients with endoscopically demonstrated peptic gastric ulcer of the lesser curvature. Six patients were treated with carbenoxolone (300 mg/day), 6 with zolimidine (1200 mg/day) and 6 with prostanoic acid (2 g/day). All of them
M C, Parodi, F, Molinari, S, Barocci
openaire +1 more source
Laboratory investigation; a journal of technical methods and pathology, 1977
The fine structure of gastric epithelial cells of normal rats and of rats restrained at low temperature has been examined by transmission and scanning electron microscopy. The observation of the normal mucosa has revealed that in comparison with the cells overlying the flat surface of the stomach, those covering the plicae have a different surface ...
C, Parisio, F, Clementi
openaire +1 more source
The fine structure of gastric epithelial cells of normal rats and of rats restrained at low temperature has been examined by transmission and scanning electron microscopy. The observation of the normal mucosa has revealed that in comparison with the cells overlying the flat surface of the stomach, those covering the plicae have a different surface ...
C, Parisio, F, Clementi
openaire +1 more source
Molecular diversity, 2017
Under solvent-free high-speed ball milling, an I[Formula: see text]-promoted condensation/cyclization of easily available methyl ketones or 1,3-dicarbonyl compounds with 2-aminopyridines has been developed, which allows the quick assembly of 2,3-substituted imidazo[1,2-a]pyridines (IPs) with broad molecular diversity, including the antiulcer drug ...
Fang-Jian, Wang +3 more
openaire +1 more source
Under solvent-free high-speed ball milling, an I[Formula: see text]-promoted condensation/cyclization of easily available methyl ketones or 1,3-dicarbonyl compounds with 2-aminopyridines has been developed, which allows the quick assembly of 2,3-substituted imidazo[1,2-a]pyridines (IPs) with broad molecular diversity, including the antiulcer drug ...
Fang-Jian, Wang +3 more
openaire +1 more source