Results 41 to 50 of about 23,624 (276)

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

open access: yesAdvanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang   +6 more
wiley   +1 more source

"Why Did "Zombie" Firms Recover in Japan?" [PDF]

open access: yes
The Japanese economy experienced prolonged recessions during the 1990s. Previous studies suggest that evergreen lending to troubled firms known as "zombie firms" distorted market discipline in terms of stabilizing the Japanese economy and caused ...
Jun-ichi Nakamura, Shin-ichi Fukuda
core   +2 more sources

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

Introduzione: Assediare gli zombi. Dal senso alla significazione [PDF]

open access: yesOcula
This contribution introduces the monographic issue "Zombesque. Sociosemiotics of a cultural epidemic," tracing the transformation of zombies from cinematic figures to pervasive cultural phenomena.
Eduardo Grillo
doaj   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang   +14 more
wiley   +1 more source

Zombies in the Posthuman Era: Hamlet, the Zombie Killer of Denmark

open access: yesNalans, 2019
The zombie figure has recently been one of the most dominant monsters in the literature of the contemporary century, especially in popular culture. In addition to hinting at the current advanced capitalist society, the zombie is also significant in ...
Zümre Gizem Yılmaz Karahan
doaj  

ZOMBIES . . . ZOMBIES EVERYWHERE: THE RISE OF ZOMBIE TV

open access: yes, 2014
Television has long been accused of creating zombies….breeding an audience that sits transfixed in front of their TV screens, hypnotized by the presumed-to-be mind-numbing qualities of this 'mindless' entertainment. This idea continues to haunt popular culture, so much so that it has been used, quite ironically, within such cult TV series as Angel (WB ...
openaire   +1 more source

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

open access: yesAdvanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen   +13 more
wiley   +1 more source

The Influence of Zombie Enterprises on Quantity and Quality of Entrepreneurship: Does Banking Competition Matter

open access: yesSAGE Open
Entrepreneurship plays a pivotal role in driving economic development and social progress. In contrast to existing literature that primarily focuses on the impact of zombie enterprises on innovation, resource distortion, and environmental pollution, this
Xiangmin He, Shenrun Yan, Jingyun Miao
doaj   +1 more source

Be Aware of Your Inner Zombie [PDF]

open access: yes, 2010
"Zombie systems" allow us to do routine things like driving to work on autopilot while we think about something else.
Porterfield, Andrew
core  

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