Results 41 to 50 of about 448 (185)

Autoreactivity Versus Autoimmunity: Characteristics of Autoantigen‐Specific CD4 T Cells in Rheumatoid Arthritis and Health

Arthritis &Rheumatology, EarlyView.
Objective CD4 T cells specific for citrullinated (cit) peptides are key players in rheumatoid arthritis (RA) immunopathogenesis. Characterizing these cells and identifying features of healthy and RA‐associated autoreactivity will provide valuable insight into disease mechanisms and form the basis of immune state biomarkers to facilitate the next ...
James A. Stanway, Daniel Peters, Helen Waller, Jeremy Lakey, Henrique De Paula Lemos, Kristian Williams, Abbie Degnan, Julie Diboll, Abdul Mannan Baru, David Tough, Arthur G. Pratt, Catharien M.U. Hilkens, Amy E. Anderson, John D. Isaacs   +13 more
wiley   +1 more source

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

Potential Risks of Virtual Influencer Diversity in Charitable Endorsements: A Cognitive Dissonance Perspective

Journal of Consumer Behaviour, EarlyView.
ABSTRACT Highlighting diversity‐related attributes has become an increasingly prominent marketing communication strategy in virtual influencer endorsement practices. Prior research has largely focused on commercial endorsement contexts, conceptualized diversity as a homogeneous and single‐dimensional construct, and emphasized its predominantly positive
Chi‐Cheng Luan, Su Zhang, I‐Lien Li
wiley   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Inflammatory Bowel Disease and Its Unique Impact on Body Image: A Qualitative Exploration

Journal of Clinical Psychology, EarlyView.
ABSTRACT Objective There is increasing interest in the relationship between inflammatory bowel disease (IBD) and body image. Quantitative research demonstrates a high level of body image dissatisfaction among individuals with IBD that is related to poorer quality of life and mental health disorders including depression, anxiety, and eating disorders ...
Mia L. Pellizzer, Réme Mountifield, Ruth Prosser, Ivanka Prichard   +3 more
wiley   +1 more source

Coping Practices of Small‐ and Medium‐Sized Enterprises Facing Power Asymmetry in Digital Platform Business

Strategic Change, EarlyView.
ABSTRACT Digital platform (DP) enterprises have risen to the top of the global economy by inverting traditional business models. They earn money through matchmaking, transaction facilitation, and efficient orchestration of other stakeholders' resources.
Lukas R. G. Fitz, Jochen Scheeg
wiley   +1 more source

Spatial Dynamics of Tourism Sustainability in EU Member States

Sustainable Development, EarlyView.
ABSTRACT This study introduces a synthetic indicator of tourism sustainability for the EU, bridging the gap between institutional monitoring and academic research. By applying the PROMETHEE II method to rank the 27 Member States in 2019 and 2023, the research transforms static data into a dynamic roadmap of post‐pandemic recovery. The findings reveal a
M. Rosario González‐Rodríguez, M. Carmen Díaz‐Fernández   +1 more
wiley   +1 more source

Formation of Distance‐Based Orientation: Political Identity through Relational Positioning in Israel

Symbolic Interaction, EarlyView.
Distance‐based orientation describes how pejorative labels may serve as anchor points for political identity. Existing research on political labeling has largely emphasized stigmatization, overlooking how labels may acquire durability and orienting capacity without losing pejorative force. Drawing on publicly circulating discourse, we trace positioning
Tammar Friedman, Asaf Saadon
wiley   +1 more source

The Hidden Hallyu Emerged: Exploring the Key Motives of Reading Adapted K‐Webtoons of South Korea

Thunderbird International Business Review, EarlyView.
ABSTRACT This study aims to investigate why global fans read Korean webtoons (K‐webtoons) and how their motivations vary across different genres. Previous studies have approached the Korean Wave (Hallyu) from a national perspective, emphasizing its influence and primarily discussing K‐pop and K‐drama.
Hoseok Gwak, Ga‐rog Han, Taehyung Kim, Minseok Kim   +3 more
wiley   +1 more source

Machine Learning and Zombie Firms Classification

Applied Sciences
We investigate whether the machine learning technique helps to identify zombie firms. We also analyze the differences in zombie indicators proposed by previous research.revious studies successfully classified firms as zombies by focusing on whether they receive subsidized credits.
Koutaroh Minami, Yukihiro Yasuda
openaire   +2 more sources