Results 81 to 90 of about 448 (185)
The share of zombie firms in Germany
, 2019 In recent years of economic slowdown and low policy rates, economies are in danger of accumulating unhealthy and unproductive firms. These zombie firms are unable to repay debt nor cover their interest obligations, kept alive by a continuous loan supply by unsound banks.
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Advanced NanoBiomed Research, Volume 6, Issue 8, August 2026.CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham +8 more
wiley +1 more source
Gamma Delta T Cells in Shrimp Allergy Express a Unique Cytotoxic Cytokine Profile
Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.ABSTRACT Shellfish allergy is the most common food allergy in adults and the third most common in children. γδ T cells have been identified as playing a critical role in antigen tolerance in allergic diseases in mouse models. In humans, γδ T cells may play a regulatory role in peanut immunotherapy, and their role in shrimp allergy remains unclear.
Brenda Bin Su +9 more
wiley +1 more source
Small, Volume 22, Issue 45, 13 August 2026.Lipid nanoparticle composition governs distinct cytokine programs through the interplay of ionizable and polyethylene glycol‐conjugated (PEGylated) lipids. In vitro profiling, design of experiments (DoE) modeling, and in vivo validation reveal how formulation can tune reactogenicity‐associated pathways, while transgene expression remains the strongest ...
Adam Alexander Walters +16 more
wiley +1 more source
VIEW, Volume 7, Issue 4, August 2026.We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen +9 more
wiley +1 more source
Criminology, Volume 64, Issue 3, Page 698-733, August 2026.Abstract We investigate how the affordances of an online context shape the processes of social learning. Using a dataset of more than 11,000 posts from the fraud subdread on the dark web forum Dread, we examine how affordances of platform governance, connectivity, anonymity, invisibility, asynchronicity, and limited oversight influence the components ...
Fangzhou Wang, Timothy Dickinson
wiley +1 more source
Assessing commitment to reflection: perceptions of medical students. [PDF]
Can Med Educ J, 2023 Poirier J +5 more
europepmc +1 more source
Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress
British Journal of Pharmacology, Volume 183, Issue 16, Page 5102-5119, August 2026.Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan +8 more
wiley +1 more source
Zombie firms and the process of natural selection
, 2022 The topic of zombie firms has become an increasingly researched topic over the years, specifically in Portugal, as zombie firms’ presence in the market is no secret, especially comparing to other European countries. In this paper, I decided to look at the presence of zombie firms in the Portuguese market over 9 years, studying their evolution and the ...
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Managed decline: Muddling through with the Sterling (dis)Agreements, 1968–74
The Economic History Review, Volume 79, Issue 3, Page 1108-1135, August 2026.Abstract How do policymakers manage the decline of an international currency? This paper revisits the view that the ‘Sterling Agreements’ of 1968–74 – bilateral contracts between the UK and sterling‐holding governments – marked a successful paradigm shift towards sterling's managed ‘retirement’.
Alan de Bromhead +3 more
wiley +1 more source