Results 71 to 80 of about 234 (216)

No mates a los zombis: diseño de un videojuego prosocial

Revista CS
En el campo de los juegos serios se entiende que estas aplicaciones informáticas se crean con fines educativos y se asume que los entornos de aprendizaje inmersivos son una característica clave en este tipo de tecnología, pero, para conseguirlo, es ...
María Elena Díaz-Rico, Manuel Alejandro Moreno-Camacho, Alejandra Herrera-Marmolejo, César Mejía   +3 more
doaj   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

On the Prospects for African Philosophy in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT This paper grapples with the situation of people of African descent in Australia by working through the constitution of the body of academic philosophy in the country. It contends with the parochialism of the Australian philosophical community and the prospects for the cultivation of greater pluralism. Taking African philosophy as one possible
Bryan Mukandi
wiley   +1 more source

Monstruos, aliens y zombis: figuraciones de la alteridad en clave semiótica

Forma y Función
La presente investigación explora las representaciones contemporáneas de monstruos, aliens y zombis como manifestaciones del imaginario actual que exploran diferentes formas de alteridad.
Carlos Andrés Arango-Lopera, María Catalina Cruz González, Daniel Aguilar Rodríguez   +2 more
doaj   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

El monstruo que succiona la energía ajena: formas de vampirismo biopolítico en la cuentística contemporánea de Paraguay

Lejana
En un época en la que aumenta el número de textos de ficción centrados en figuras de monstruos, fantasmas, seres deformes y zombis y en la que la representación de la deformidad y la desviación refleja una finalidad “política” de reivindicar formas de ...
Giuseppe Gatti
doaj   +1 more source

Autoreactivity Versus Autoimmunity: Characteristics of Autoantigen‐Specific CD4 T Cells in Rheumatoid Arthritis and Health

Arthritis &Rheumatology, EarlyView.
Objective CD4 T cells specific for citrullinated (cit) peptides are key players in rheumatoid arthritis (RA) immunopathogenesis. Characterizing these cells and identifying features of healthy and RA‐associated autoreactivity will provide valuable insight into disease mechanisms and form the basis of immune state biomarkers to facilitate the next ...
James A. Stanway, Daniel Peters, Helen Waller, Jeremy Lakey, Henrique De Paula Lemos, Kristian Williams, Abbie Degnan, Julie Diboll, Abdul Mannan Baru, David Tough, Arthur G. Pratt, Catharien M.U. Hilkens, Amy E. Anderson, John D. Isaacs   +13 more
wiley   +1 more source

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

El secreto de Hollywood: zombis creados con nanobots cerebrales

Revista de Medicina y Cine / Journal of Medicine and Movies, 2018
Recientemente se está realizando una sorprendente campaña para alertar al mundo de una próxima epidemia de zombies, “la zombificación” es considerada “como una infección que es transmitida por un virus, sin embargo, unanálisis científico objetivo, lleva ...
David SALINAS FLORES
doaj  

Re-casting la revolución: El héroe popular en Juan de los muertos

Rebeca, 2016
A finales de los años sesenta el cine cubano mostraba su primer héroe popular: Juan Quin Quin. Este personaje que progresivamente iba pasando de campesino pícaro a guerrillero comprometido con la liberación del pueblo debía mostrar el corazón de la ...
Omar Rodriguez
doaj   +1 more source