Results 101 to 110 of about 73,802 (257)

PRECARIZED AGEING‐IN‐PERIFERIA: Low‐Income Older Adults in a Transforming Neighbourhood

International Journal of Urban and Regional Research, EarlyView.
Abstract In this article we investigate how intersecting forms of precarity shape the everyday practices of ageing‐in‐place developed by low‐income older adults in Via Milano, a historically segregated yet rapidly transforming neighbourhood in Brescia, northern Italy. We draw on qualitative and ethnographic research to examine how diverse urban changes—
Marco Alioni, Barbara Badiani
wiley   +1 more source

Towards the Democratisation of Care? Insights From Co‐Governance in Local Welfare in Spain and Italy

The British Journal of Sociology, EarlyView.
ABSTRACT The organisation and distribution of care responsibilities represent a central issue in contemporary welfare debates. Although welfare systems have progressively sought to socialise care related risks tackling distribution's inequality, the organisation of care services received less attention.
Francesca Donati, María Jesús Rodríguez‐García   +1 more
wiley   +1 more source

Genome Expansion of ZPB1(a) and ZPC1(a) in Basal Species or Liver Expression of ZPB1a and ZPC1aa in Advanced Species, Two Different Strategies to Ensure Sufficient ZP Synthesis in Teleosts

Integrative Zoology, EarlyView.
We found that teleosts employed two different strategies to ensure sufficient ZP (zona pellucida) synthesis: expansion of ZPB1(a) and ZPC1(a) in basal species or liver expression of ZPB1a and ZPC1aa in advanced species. The N‐terminus of expanded ZPB1(a) or ZPC1(a) and liver‐expressed ZPB1a contains repeated units or low‐complexity regions to form ...
Tian Gao, Suying Ma, Shiyi Zhang, Fan Bai, Lingyao Gan, Wenjing Tao, Feilong Wang, Deshou Wang, Lina Sun   +8 more
wiley   +1 more source

Common ground: Efficient, consistent, observer‐independent bioacoustic call density estimation with adjudicated ground truth and capture–recapture detection functions

Methods in Ecology and Evolution, EarlyView.
Abstract Passive acoustic recording is a cost‐effective method for monitoring vocal animals. Within this field, there is an increasing focus on automated detection algorithms for counting calls and estimating call density (in space and time). For accurate interpretation of such results, it is important to understand and correct biases introduced by ...
Brian S. Miller, Nat Kelly, Meghan G. Aulich, Naysa Balcazar, Susannah Buchan, Franciele R. de Castro, Kym Reeve, Danielle V. Harris   +7 more
wiley   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

Hyperactivation and Tyrosine Phosphorylation of Cryopreserved Stallion Spermatozoa in Relation to Conventional In Vitro Fertilization Blastocyst Production

Andrology, EarlyView.
ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro, Carolina C. Porflidt, Alexandra L. Ash, Jacobo S. Rodriguez, Perla D. Fleury, Edward L. Squires, Elaine M. Carnevale   +6 more
wiley   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Atrial natriuretic peptide counteracts aldosterone secretion by preventing acute angiotensin II‐induced cAMP signalling

British Journal of Pharmacology, EarlyView.
Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar, Egor B. Skryabin, Bettina M. Buchholz, Michaela Kuhn, Celso E. Gomez‐Sanchez, Stepan Gambaryan, Viacheslav O. Nikolaev   +6 more
wiley   +1 more source

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

Zona et vaccination contre le zona

Primary and hospital care: médecine interne générale, 2023
Lea Pajarola, Sarah Gruson, Bernhard Wingeier, Caesar Gallmann, Gisela Etter, Emanuel Steinhauer, Patrick Zürcher, Matthias Berger, Katia Boggian, Philip Tarr   +9 more
openaire   +1 more source