Results 51 to 60 of about 953,310 (267)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Common Sleeping Related Problems and Illnesses of Persons who Stayed within Geopathic Stress Zone
JPAIR, 2012 The study attempted to determine the common sleeping related problems and illnesses among persons who stayed for a period of time within geopathic stress (GS) zone. This descriptive research was conducted in November 2008 to April 2009 among conveniently
Jeremias L. Convocar
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Ramp - Metering Algorithms Evaluated within Simplified Conditions
Civil and Environmental Engineering, 2017 Freeway networks reach their limits, since it is usually impossible to increase traffic volumes by indefinitely extending transport infrastructure through adding new traffic lanes.
Janota Aleš +3 more
doaj +1 more source
Tataloka, 2016 The purposes of this research are to analyze the pattern of coastal spatial changes in Kendal Regency from 1910 to 2009, and to formulate coastal area zoning plan based on spatial changes. The Method of analysed was with overlay technique.
Tjaturahono Budi Sanjoto +2 more
doaj +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Зерновое хозяйство России, 2018 The priority of grain use is usually determined by its great social significance which allows solving the task of food supply, especially with bread. Winter wheat as a main food crop takes up 38,6% in grain production of KBR and has a major effect on the
Kh. A. Malkanduev +3 more
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Incidence des codes miniers sur l’exploitation des minerais stratégiques en RD Congo. Cas du commerce de Coltan et de Cobalt [PDF]
Mouvements et Enjeux Sociaux, 2023 Cette étude montre que les ressources minières dont dispose le sous-sol congolais ont toujours attiré les convoitises des chercheurs, explorateurs et investisseurs venant de différents horizons depuis l'époque coloniale jusqu’à ce jour. C’est ainsi que l'
Gracia MAYOKA MENAMA +4 more
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