Results 31 to 40 of about 99,505 (245)

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Role of soft tissue and bone interactions in the developmental integration and modularity of the skull in neural crest‐specific gap junction alpha‐1 knockout mice

The Anatomical Record, EarlyView.
Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore, Madeline Tourigny, Diana Quinonez, Kevin Barr, Matthew W. Grol, Katherine E. Willmore   +5 more
wiley   +1 more source

Accès aux soins de santé pour les enfants de 0 à 5 ans dans la zone de santé de Kikwit Sud, République Démocratique du Congo : Perspectives des parents, déterminants et solutions

Revue Congolaise des Sciences et Technologies
Les politiques publiques internationales visent à rendre l'accès aux soins de santé homogène, assurant à l'ensemble de la population une égalité d'accès. Cependant, environ 1,4 milliard de personnes dans le monde n'ont toujours pas accès aux services de
Eugénie Kiniangi Keza, Samuel Bapidia Nzengu, Steve Botomba Ntambwe, Yves Mafuta Vampeke, Leyka Mukandu Basua Babintu, Augustin Tshitadi Makangu   +5 more
doaj   +1 more source

Utilisation des méthodes contraceptives modernes en République Démocratique du Congo: prévalence et barrières dans la zone de santé de Dibindi à Mbuji-Mayi

The Pan African Medical Journal, 2017
INTRODUCTION: l'bjectif de cette étude était de déterminer la prévalence contraceptive moderne et les barrières à l'tilisation des méthodes contraceptives modernes chez les couples de la Zone de Santé Dibindi, à Mbuji-Mayi en République Démocratique du ...
Abel Mukengeshayi Ntambue, Rachel Ngalula Tshiala, Franéoise Kaj Malonga, Tabitha Mpoyi Ilunga, Josaphat Mulumba Kamonayi, Simon Tshimankinda Kazadi, Charles Matungu Matungulu, Angel Nkola Musau, Diese Mulamba, Michéle Dramaix-Wilmet, Philippe Donnen   +10 more
doaj   +1 more source

Les Organisations de la Société Civile et la Lutte Contre la Pauvreté en Afrique Subsaharienne [PDF]

, 2004
The paper presents the role played by civil society organisations to bring down the ...
Aurélien C. Atidegla, Celestin Hounkpe, Elisabeth Paul, Gregor Stangherlin, Latifou Yessoufou, Magloire Cossou, Marc Labie, Marc Poncelet, Marthe Nyssen, Mathieu Soglonou, Pascal Wele, Simon-Narcisse Tomety   +11 more
core  

Estimation du nombre de naissances et structuration de l'offre vaudoise dans le domaine de l'obstétrique, horizons 2020-2030 [PDF]

, 2016
Le nombre de naissances augmente régulièrement dans le canton de Vaud depuis plusieurs années (7'265 en 2004 à 8'277 en 2012). Selon les projections de Statistique Vaud le nombre de naissances devrait continuer de croitre d'ici 2030.
Bize, R., Henry, B., Moreau, A., Oettli, A.   +3 more
core   +1 more source

Lifelong evolution of autoreactive plasma cell numbers, affinity and anatomical location in arthritic K/BxN mice

Arthritis &Rheumatology, Accepted Article.
Objective The spontaneous K/BxN mouse model of rheumatoid arthritis has been used extensively to study chronic inflammation, contribution of immune cells, and the primordial role of autoreactive antibodies in disease initiation and severity. Only the ubiquitous enzyme glucose‐6‐phosphate isomerase (GPI) is the target of IgG autoantibodies secreted by ...
Thibault Vanhoucke, Carlos Castrillon, Odile Richard‐Le Goff, Angga Perima, Matteo Broketa, Andrew D. Griffiths, Patrick England, François Huetz, Pierre Bruhns   +8 more
wiley   +1 more source

EU Neighbourhood policy: implications for public services and trade unions [PDF]

, 2006
The EU Neighbourhood policy creates pressures to liberalise and privatise public services.
Hall, David
core  

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Diaspora, Développement et Citoyenneté: Les Migrants Originaires du Bassin du Fleuve Sénégal [PDF]

, 2005
The author analyses the contribution of the diaspora on the development of their ...
Olivier le Masson, Samba Yatera
core