Results 31 to 40 of about 5,680,084 (309)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Comparison of 5-year progression of retinitis pigmentosa involving the posterior pole among siblings by means of SD-OCT: a retrospective study

open access: yesBMC Ophthalmology, 2018
Background The aim of this study is to analyze and compare the progression of photoreceptor atrophy among siblings affected by retinitis pigmentosa by means of spectral SD-OCT.
Leonardo Colombo   +7 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Dealer on-line registration system

open access: yes, 1999
Rev. 10/99; Title from cover.; "Dealer On-Line Procedure Manual"--Intro.; Accompanied by 1 sheet of automobile registration cards and 1 application for duplicate certificate of title, with cover sheet.; Harvested from the web on 11/13 ...
Connecticut. Dept. of Motor Vehicles. Dealers and Repairers Division.
core   +4 more sources

Study of shear-plastic slip mechanism based on TC4 titanium alloy.

open access: yesPLoS ONE
The stagnation point and dead metal zone in the cutting process directly or indirectly affect the chip formation and stress distribution, while the stress distribution in the machining process determines the plastic slip direction of the material. Aiming
Bo Hu   +5 more
doaj   +1 more source

Opposing shear senses in a subdetachment mylonite zone: Implications for core complex mechanics [PDF]

open access: yes, 2010
Global studies of metamorphic core complexes and low‐angle detachment faults have highlighted a fundamental problem: Since detachments excise crustal section, the relationship between the mylonitic rocks in their footwalls and the brittle deformation in ...
Frances J. Cooper   +9 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Interim Coastal Zone Study Committee, Galveston, Texas, January 14, 1972

open access: yes, 1972
28 pagesTranscript of the Interim Coastal Zone Study Committee meeting held on January 14, 1972, in Galveston ...
Interim Coastal Zone Study Committee
core   +1 more source

Establishing a low-risk zone for a temporary extra-articular calcaneo-tibial pin fixation in an unstable ankle or subtalar joint

open access: yesScientific Reports, 2022
This study aimed to establish a low-risk zone to avoid neurovascular injury during a temporary extra-articular calcaneo-tibial pin fixation in an unstable ankle or subtalar joint.
Ik Yang   +4 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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