Results 91 to 100 of about 751,195 (373)
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit+19 more
wiley +1 more source
Purchasing Copy, Printing and Scanning Services in Zurich [PDF]
Zurich is the largest Swiss city with approximately 400,000 inhabitants and an annual public procurement budget of over 1.6 billion. Sustainability has been a specific target on the City's political agenda since 1998.
core
Application of the Zoom Meeting Application in Online Learning During the Pandemic
In the midst of the Covid-19 pandemic outbreak, almost all Indonesians, including Bengkulu province, expect to experience the spike in positive cases of Covid-19, particularly in the Rejang Lebong Regency, resulting in many very significant changes in ...
semanticscholar +1 more source
Zoom in, zoom out: Geographic scale and multinational activity [PDF]
IB scholars have long studied the multinational enterprise (MNE) and now recognize that its ability to capture value stems from its control of bottleneck assets. In contrast, economic geographers and regional scientists have largely focused their attention on the locations within which economic and business systems operate.
Lee Li+5 more
openaire +2 more sources
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
Coordination among multiple interdependent processes and stakeholders and the allocation of optimal resources make enterprise systems management a challenging process.
Shinoy Vengaramkode Bhaskaran
doaj +1 more source
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada+3 more
wiley +1 more source
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper+5 more
wiley +1 more source
The study contributes to the nascent digital academic writing tutoring field by applying posthuman thinking while investigating intimate socio-material relations during a participatory action research project. Due to the COVID-19 pandemic (2020–2021), on-
Charlotta Hilli, Sofia Jusslin
doaj
Editorial: To zoom or not to zoom – that is the question [PDF]
Sam Nishanth Gnanapragasam+2 more
openaire +4 more sources