Results 41 to 50 of about 146,349 (266)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Optimization Of Video Conference With Priority Features On The Mikrotik Router

open access: yesComputer Science, 2022
Munculnya standar baru yang harus dipenuhi oleh semua aktor. Akses mudah ke konferensi video memiliki banyak aspek positif yang akhirnya menjadi kebutuhan saat ini.
Eka Kusuma Pratama   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

EnterpriseAI: A Transformer-Based Framework for Cost Optimization and Process Enhancement in Enterprise Systems

open access: yesComputers
Coordination among multiple interdependent processes and stakeholders and the allocation of optimal resources make enterprise systems management a challenging process.
Shinoy Vengaramkode Bhaskaran
doaj   +1 more source

DIFFRACTING HYBRID DIDAKTIK – RELATIONAL, FLUID, AND FRAGMENTED DIGITAL WRITING TUTORING IN HIGHER EDUCATION

open access: yesDigital Culture & Education, 2023
The study contributes to the nascent digital academic writing tutoring field by applying posthuman thinking while investigating intimate socio-material relations during a participatory action research project. Due to the COVID-19 pandemic (2020–2021), on-
Charlotta Hilli, Sofia Jusslin
doaj  

Creating a Virtual Writing Center to Support Self-Regulated Learning

open access: yesStudies in Self-Access Learning Journal, 2020
The Covid-19 pandemic has disrupted traditional approaches to education and forced educators to adopt and adapt technologies to allow institutions to remain open, offer courses and other services to enable students to continue their education. This rapid
Chris Harwood, Dennis Koyama
doaj   +1 more source

Accents in Speech Recognition through the Lens of a World Englishes Evaluation Set

open access: yesResearch in Language, 2023
Automatic Speech Recognition (ASR) systems generalize poorly on accented speech, creating bias issues for users and providers. The phonetic and linguistic variability of accents present challenges for ASR systems in both data collection and modeling ...
Miguel Del Río   +11 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

The Design and Positioning Method of a Flexible Zoom Artificial Compound Eye

open access: yesMicromachines, 2018
The focal lengths of the sub-eyes in a single-layer uniform curved compound eye are all the same, resulting in poor imaging quality for the compound eye.
Lun Li   +4 more
doaj   +1 more source

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