Invisible and ignored: lifting the lid on the problems of endemic zoonosez [PDF]
, 2015 No abstract ...
Halliday, Jo +2 more
core
FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis
Advanced Science, EarlyView.ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li +16 more
wiley +1 more source
Zoonosis emergence linked to agricultural intensification and environmental change [PDF]
, 2013 A systematic review was conducted by a multidisciplinary team to analyze qualitatively best available scientific evidence on the effect of agricultural intensification and environmental changes on the risk of zoonoses for which there are epidemiological ...
Artois +59 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv +8 more
wiley +1 more source
Candida haemulonii Species Complex: Emerging Fungal Pathogens of the Metschnikowiaceae Clade
Zoonoses, 2023 Candida species, the most common fungal pathogens affecting humans, cause not only superficial infections but also life-threatening invasive infections, particularly in immunocompromised individuals. Although Candida albicans remains the most frequent
Chengjun Cao +4 more
doaj +1 more source
Methods for prioritization: Toward quantitative approach to prioritize zoonoses in South East Asia [PDF]
, 2011 Resources for research, surveillance, control and others public health activities are limited and it is difficult to compare the importance of diseases, which vary in terms of occurrence, impacts, etc. So, in this context of scarce resources and multiple
Bordier, Marion +3 more
core
Animal and human health: tackling uncertainty through participatory modelling and simulation [PDF]
, 2017 Zoonoses–infectious diseases communicable between animals and humans–, drug resistance and environmental pollution are now causing serious health problems worldwide.
Binot, Aurélie, Duboz, Raphaël
core +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Report on the evaluation of surveillance systems relevant to zoonotic diseases in Kenya, 2015: A basis for design of an integrated human–livestock surveillance system [PDF]
, 2019 The Zoonoses in Livestock in Kenya (ZooLinK) is a project that seeks to enable Kenya develop an effective surveillance programme for zoonotic diseases (infectious diseases transmissible between animals and human beings).
Ndeda, C., Ngere, I., Omondi, M.
core
Advanced Science, EarlyView.Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun +11 more
wiley +1 more source