Results 91 to 100 of about 37,096 (257)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Pasteurella lipoprotein E interacts with host ABCF2 to facilitate adhesion and cell apoptosis

mLife, EarlyView.
Abstract Pasteurella multocida can cause serious diseases in many animal species and humans, yet the mechanisms of its pathogenesis remain to be elucidated. In this study, we found that the lipoprotein E (PlpE) of P. multocida contributed to bacterial adhesion to host cells.
Yuyao Shang, Fei Wang, Menghan Chen, Zihao Wang, Hanyuan Liu, Lin Hua, Huanchun Chen, Bin Wu, Zhong Peng   +8 more
wiley   +1 more source

Characterising fine‐scale habitat associations for range expanding species with limited data: a case study on the West Nile Virus vector, Culex modestus

Oikos, EarlyView.
The ecological and epidemiological consequences of species expanding into new areas are growing concomitantly with climate change. Those aiming to monitor species expanding in range must make optimal use of finite resources to deliver effective surveillance capable of detecting new incursions and range expansions.
Susanna Cant, Owen Jones, Maisie Vollans, Maximilian Ayling, Nyall Jamieson, Alexander G. C. Vaux, Jolyon M. Medlock, Thomas Ward, Julie Day, Robert S. Paton   +9 more
wiley   +1 more source

Dual glycosylation of wall teichoic acid modulates the O‐antigen pattern and virulence in serovar 4b Listeria monocytogenes

mLife
Among the 14 serovars of Listeria monocytogenes (Lm), serovar 4b strains are the most predominant isolates linked to human listeriosis outbreaks‐a phenotype associated with their unique wall teichoic acid (WTA) decorated with galactose (Gal) and glucose (
Hao Yao, Yuting Wang, Ruochen Wang, Zhengnan Dong, Zhenhua Wu, Luyong Wang, Yuelan Yin, Xin'an Jiao   +7 more
doaj   +1 more source

Urban wild meat and pangolin consumption across southern forested Cameroon: The limited influence of COVID‐19

People and Nature, EarlyView.
Abstract Overexploitation of wildlife is pervasive in many tropical regions, and in addition to being a significant conservation and sustainability concern, it has received global attention given discussions over the origins of zoonotic disease outbreaks.
Franklin T. Simo, Ghislain F. Difouo, Christian N. Tchana, Alain Christel Wandji, Alfiery Laurel Djomnang‐Nkwala, Marcelle Mbadjoun Nziké, Sévilor Kekeunou, Markéta Swiacká, Daniel J. Ingram   +8 more
wiley   +1 more source

The effects of anti-lung cancer in nude mice by a fully human single-chain antibody against associated antigen Ts7TMR between A549 cells and Trichinella spiralis

Artificial Cells, Nanomedicine, and Biotechnology
Lung cancer is a dangerous disease that is lacking in an ideal therapy. Here, we evaluated the anti-lung cancer effect in nude mice of a fully human single-chain antibody (scFv) against the associated antigen 7 transmembrane receptor (Ts7TMR), which is ...
Taotao Yue, Jinpeng Wang, Fang Liu, Pengtao Gong, Jianhua Li, Xichen Zhang, Nan Zhang   +6 more
doaj   +1 more source

The importance of wild meat and freshwater fish for children's nutritional intake in the Congo Basin

People and Nature, EarlyView.
Abstract Wild meat and freshwater fish are widely consumed in the Congo Basin, but in some areas, they are at risk of disappearing due to unsustainable hunting and fishing and changes in their habitat. Wild meat is also at risk of being eliminated from local diets due to potential policy changes such as wild meat bans.
Amy Ickowitz, Muhammad Faisal Pratama, Mahdiyatur Rahmah, Caleb Yengo Tata, Erasmus Nchuaji Tang, Judith Laure Ngondi, Victor Buhendwa Mirindi   +6 more
wiley   +1 more source

How uneven access shapes the socio‐economic and environmental potential of game meat value chains: The case of legal game meat in Zambia

People and Nature, EarlyView.
Abstract Game meat contributes to human nutrition, food security and sociocultural practices around the world. Game meat also comes with risks, including overharvesting and zoonotic and food‐borne disease. These may be pronounced where game meat travels along complex value chains from rural to urban areas.
Brock Bersaglio, Charis Enns, Edgar Hichoonga, Francis Masse, Matt Sommerville, Nathalie van Vliet   +5 more
wiley   +1 more source

The impact of COVID‐19 on public perceptions of wild meat in Central Africa

People and Nature, EarlyView.
Abstract Wild meat is a significant source of food and income generation in Central Africa. However, there is little knowledge of how the assumed link between COVID‐19 and wild meat consumption has been discussed by the media and received by the public. In this study, we conducted media content analysis of 264 articles published in 2019–2020 related to
Yuhan Li, Lude Kinzonzi, Paul Loundou, Divin Malekani, Krossy Mavakala, Christian Mikolo Yobo, Katharine Abernethy, Matilda Eve Dunn, Donald Midoko Iponga, Robert Mwinyihali, Joss Wright, Eleanor Jane Milner‐Gulland, Lauren Coad, Juliet H. Wright, Daniel W. S. Challender   +14 more
wiley   +1 more source

More than proteins for empty stomachs: Wild meat in the BaTonga food system

People and Nature, EarlyView.
Abstract Our paper highlights the limitations of the framework used by many conservation‐focused programmes that incorporate food security objectives. This framework encourages the substitution of wild proteins with domestic proteins by promoting animal farming in communities located near conservation areas.
Muriel Figuié, Luzibo Ottilia Munsaka, Vupenyu Dzingirai, Olivier Lepiller, Maxwell Phiri, Patrice Grimaud   +5 more
wiley   +1 more source