Results 131 to 140 of about 88,866 (346)

The evolutionary landscape and serotypic dynamics of avian infectious bronchitis virus from spike protein

iMetaOmics, EarlyView.
This study integrates two decades of surveillance with genomic and structural analyses to decipher how spike protein glycosylation haplotypes drive avian coronavirus evolution. We uncover how specific glycosylation patterns associate with receptor‐binding affinity, shape global transmission dynamics, and correlate with clinical outcomes.
Hao Zhang, Zongxi Han, Chuangchao Zou, Yihui Huang, Shiping Sun, Ouyang Peng, Usama Ashraf, Qiuping Xu, Yao Ge, Qixiang Kang, Xiuli Ma, Xinheng Zhang, Ye Zhao, Xin Yang, Hongning Wang, Guozhong Zhang, Qingmei Xie, Mang Shi, Yongsen Ruan, Min Liao, Shengwang Liu, Yongchang Cao   +21 more
wiley   +1 more source

Methodology of the biological risk classification of animal pathogens in Belgium [PDF]

, 2010
The biological hazards posed by micro-organisms have lead to their categorisation into risk groups and the elaboration of classification lists. Current classification systems rely on criteria defined by the World Health Organization, which cover the ...
Boyen, Filip, Declercq, K, Desmecht, D, Herman, P, Koenen, F, Pauwels, K, Quanten, K, Thiry, J, Van Vaerenbergh, B   +8 more
core   +1 more source

Modeling Factors Associated With Diarrhea Caused by Cryptosporidium Species Using Machine Learning Methods

Journal of Clinical Laboratory Analysis, EarlyView.
This study applies machine learning methods, specifically Random Forest and Bagged CART, to classify Cryptosporidium spp. infections among children and identify key risk factors. The Bagged CART model demonstrated superior sensitivity and predictive performance, highlighting household crowding and water source as the most influential determinants of ...
Türkan Mutlu Yar, Zeynep Küçükakçali, Ülkü Karaman   +2 more
wiley   +1 more source

Eczema Monkeypoxicum Following Sexual Transmission Treated With Tecovirimat

JEADV Clinical Practice, EarlyView.
ABSTRACT Mpox is a zoonotic viral infection caused by monkeypox virus (MPXV) and risk factors for its dissemination include previous dermatoses such as atopic dermatitis [1]. We present the case of a 30‐year‐old male with an unusual and extensive presentation of mpox following unprotected sexual intercourse, with an excellent response to tecovirimat ...
Andrés Vidal González, Sergio López Alcázar, José Ángel Amat Sánchez, Francisco Vergara Barria, Rosa Feltes Ochoa, Elena Sendagorta Cudos, Pedro Herranz Pinto   +6 more
wiley   +1 more source

Dual glycosylation of wall teichoic acid modulates the O‐antigen pattern and virulence in serovar 4b Listeria monocytogenes

mLife
Among the 14 serovars of Listeria monocytogenes (Lm), serovar 4b strains are the most predominant isolates linked to human listeriosis outbreaks‐a phenotype associated with their unique wall teichoic acid (WTA) decorated with galactose (Gal) and glucose (
Hao Yao, Yuting Wang, Ruochen Wang, Zhengnan Dong, Zhenhua Wu, Luyong Wang, Yuelan Yin, Xin'an Jiao   +7 more
doaj   +1 more source

Invisible and ignored: lifting the lid on the problems of endemic zoonosez [PDF]

, 2015
No abstract ...
Halliday, Jo, Hampson, Katie, Lembo, Tiziana   +2 more
core  

Polydopamine‐Antibiotic Composite Coating for Antibiofilm Applications

Macromolecular Bioscience, EarlyView.
Antibiotic‐loaded polydopamine coatings are developed to combat biofilm‐forming bacteria on catheter surfaces. These coatings strongly inhibit Pseudomonas aeruginosa biofilm formation on diverse materials, including during continuous artificial‐urine flow, and can accommodate multiple antibiotics.
Gillian A. Kropp, Hannah Q. Karp, Jayasimha Rao, Henriette Suzanne Muller, Nammalwar Sriranganathan, Elizabeth S. Nowak, Michael D. Schulz   +6 more
wiley   +1 more source

Ruthenium‐Catalyzed CH Alkenylation of Trypanocidal Naphthoquinones: A Mechanistic Benchmarking Study

ChemistryOpen, EarlyView.
Computational roadmap to click‐ready quinones. Quantum chemical analysis reveals how substituents modulate the reactivity of trypanocidal naphthoquinones in Ru‐catalyzed CH alkenylation, guiding the design of sulfonyl‐fluoride scaffolds for next‐generation antiparasitic agents.
Esther R. S. Paz, Cauê P. Souza, Joyce C. De Oliveira, Renata G. Almeida, Chonny Herrera‐Acevedo, Sulaiman Lakoh, Guilherme A. M. Jardim, Eufrânio N. da Silva Júnior, Felipe Fantuzzi   +8 more
wiley   +1 more source

The effects of anti-lung cancer in nude mice by a fully human single-chain antibody against associated antigen Ts7TMR between A549 cells and Trichinella spiralis

Artificial Cells, Nanomedicine, and Biotechnology
Lung cancer is a dangerous disease that is lacking in an ideal therapy. Here, we evaluated the anti-lung cancer effect in nude mice of a fully human single-chain antibody (scFv) against the associated antigen 7 transmembrane receptor (Ts7TMR), which is ...
Taotao Yue, Jinpeng Wang, Fang Liu, Pengtao Gong, Jianhua Li, Xichen Zhang, Nan Zhang   +6 more
doaj   +1 more source

A Rare Primary Pelvic Hydatid Cyst Presenting as Sciatica [PDF]

, 2012
Primary hydatid cyst in the pelvis is rare, and usually presents with pressure symptoms affecting the adjacent abdominal organs. We describe a rare hydatid cyst which was eroding the sacral hallow, protruding into the right sciatic foramen and presenting
Bafna, UD, Devi, UK, Rathod, PS, Reddihalli, PV   +3 more
core