Results 41 to 50 of about 268,909 (312)

Molecular evidence for zoonotic transmission of Giardia duodenalis among dairy farm workers in West Bengal, India [PDF]

, 2011
No study in the past has examined the genetic diversity and zoonotic potential of Giardia duodenalis in dairy cattle in India. To assess the importance of these animals as a source of human G.
Amiya Kumar Pramanik, Buret, Caccio, Chanchal Debnath, Deshpande, Ey, Hall, Higgins, Huetink, Islam, Itagaki, Lalle, Langkjaer, Lasek-Nesselquist, Lihua Xiao, Mendonca, Monis, Olson, Olson, O’Handley, O’Handley, Ruest, Sandipan Ganguly, Shahbaz Manzoor Khan, Thompson, Tomoyoshi Nozaki, Trout, Trout, Winkworth, Xiao, Xiao   +30 more
core   +1 more source

Prompt Response to a Cross-border Plague Outbreak in Zombo District, Minimized Spread, Uganda, March 2019

Journal of Interventional Epidemiology and Public Health, 2022
Introduction: Plague, which is caused by the bacterium Yersinia pestis, is a priority zoonotic disease targeted for elimination in Uganda. On 6 March 2019, the Uganda Ministry of Health was notified of a patient in Zombo District with clinical ...
Doreen Nsiimire Gonahasa, Bernadette Mirembe Basuta, Sandra Nabatanzi, Benon Kwesiga, Lilian Bulage, Uganda Public Health Fellowship Program, Ministry of Health, Kampala, Uganda   +5 more
doaj   +1 more source

Preparation for the next pandemic: challenges in strengthening surveillance

Emerging Microbes and Infections, 2023
The devastating Coronavirus Disease 2019 (COVID-19) pandemic indicates that early detection of candidates with pandemic potential is vital. However, comprehensive metagenomic sequencing of the total microbiome is not practical due to the astronomical and
Kelvin Hei-Yeung Chiu, Siddharth Sridhar, Kwok-Yung Yuen   +2 more
doaj   +1 more source

Mutated COVID-19 may foretell a great risk for mankind in the future

New Microbes and New Infections, 2020
Coronavirus disease 2019 SARS-CoV-2 (COVID-19) is a zoonotic virus causing a variety of severe respiratory diseases. SARS-CoV-2 is closest to SARS-CoV and MERS-CoV in structure.
A.A. Dawood
doaj   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Cost-effectiveness of chikungunya vaccination with the live attenuated vaccine in U.S. territories

npj Vaccines
A live attenuated chikungunya vaccine, IXCHIQ, was approved in the United States in 2023 for use in adults. We assessed the cost-effectiveness of two different vaccination strategies, routine and outbreak vaccination, for persons aged ≥18 years living in
Kelly Kilburn, Martin I. Meltzer, Seonghye Jeon, Bishwa B. Adhikari, Nicole Lindsey, Susan L. Hills, J. Erin Staples   +6 more
doaj   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

Individual-level factors associated with the risk of acquiring human Plasmodium knowlesi malaria in Malaysia: a case-control study [PDF]

, 2017
Background: The emergence of human malaria due to the monkey parasite Plasmodium knowlesi threatens elimination efforts in southeast Asia. Changes in land use are thought to be driving the rise in reported P knowlesi cases, but the role of individual ...
Anstey, Nicholas M., Barber, Bridget E., Brock, Patrick M., Cox, Jonathan, Drakeley, Christopher J., Fornace, Kimberly M., Grigg, Matthew J., Jelip, Jenarun, von Seidlein, Lorenz, William, Timothy, Yeo, Tsin W.   +10 more
core   +3 more sources

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Variable geographic distribution of Blastocystis subtypes and its potential implications. [PDF]

, 2013
Blastocystis is a common intestinal micro-eukaryote found in both humans and non-human hosts and known to be genetically very diverse. It has been divided into numerous subtypes (STs), nine of which have been identified in humans to date.
Alfellani, Mohammed A, Clark, C Graham, Fagbenro-Beyioku, Adetayo F, Onuoha, Emeh Sunday Uche, Stensvold, C Rune, Vidal-Lapiedra, Amparo   +5 more
core   +1 more source