Results 91 to 100 of about 1,245,941 (309)

One Health – an Ecological and Evolutionary Framework for tackling Neglected Zoonotic Diseases [PDF]

, 2015
Understanding the complex population biology and transmission ecology of multihost parasites has been declared as one of the major challenges of biomedical sciences for the 21st century and the Neglected Zoonotic Diseases (NZDs) are perhaps the most ...
Adamo, Akopyants, Anderson, Antia, Azevedo, Berry, Betson, Biswas, Boatin, Boissier, Chargui, Civetello, Cleaveland, Combes, Consortium* THG, Crichton, Criscione, Cutillas, Delgado, Detwiler, Dobson, Doby, Dunams-Morel, Eberhard, Fan, Faye, Fenton, Fenton, Fraga de Azevedo, Funk, Garba, Gaunt, Gelanew, Genis, Gibbs, Gibson, Gouvras, Gretillat, Grigg, Gupta, Hahn, Hahn, Hanelt, Hargrove, Haydon, Hotez, Hotez, Huyse, Huyse, Inpankaew, Johnson, Jolles, Kaushik, Kaushik, Keesing, Kelly, Kilpatrick, King, Klepac, Koukounari, Lamberton, Laval, Le, Leger, Lembo, Liang, Liese, Lloyd-Smith, Lu, Lu, Lu, Lu, Lustigman, Machado, Maia, Mathews, Mavarez, Messenger, Messenger, Miles, Molyneux, Moné, Muhanguzi, Muller-Graf, Mupfasoni, Norton, Pardo-Diaz, Parrish, Pedersen, Perez-Quintero, Ramiro, Randolph, Ravel, Robinson, Rogers, Rollinson, Rudge, Rudge, Rudge, Salkeld, Saroufim, Silva Oliveira, Smith, Steinauer, Strauss, Streicker, Streicker, Sturm, Taylor, Theron, Theron, Tomley, UNDP, Viana, Volf, Wang, Webby, Webster, Webster, Webster, Webster, Webster, Webster, Welburn, Welburn, Whitlock, WHO, Wood, Woolhouse, Woolhouse, Woolhouse, Woolhouse, Woolhouse, Yamane, Yamane, Zhou   +135 more
core   +4 more sources

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, EarlyView.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Occurrence of potentially zoonotic and cephalosporin resistant enteric bacteria among shelter dogs in the Central and South-Central Appalachia

BMC Veterinary Research, 2021
Background Antimicrobial resistance and presence of zoonotic enteropathogens in shelter dogs pose a public health risk to shelter workers and potential adopters alike.
A. Verma, K. Carney, M. Taylor, Kaitlyn Amsler, Joey Morgan, K. Gruszynski, E. Erol, C. Carter, Stephan J. Locke, Ashton Callipare, D. Shah   +10 more
semanticscholar   +1 more source

EasyAmplicon 2: Expanding PacBio and Nanopore Long Amplicon Sequencing Analysis Pipeline for Microbiome

Advanced Science, EarlyView.
EasyAmplicon 2 is an updated, user‐friendly, and community‐supported pipeline designed for full‐length amplicon data from long‐read sequencing technologies such as PacBio and Nanopore. It supports multiple platforms (Illumina, PacBio, Nanopore, etc.), integrates tools like DADA2 and Emu, and offers a complete workflow from raw data processing to high ...
Hao Luo, Defeng Bai, Zhihao Zhu, Salsabeel Yousuf, Haifei Yang, Jiani Xun, Meiyin Zeng, Yao Wang, Yunyun Gao, Kai Peng, Shanshan Xu, Yuanping Zhou, Tianyuan Zhang, Chuang Ma, Huiyu Hou, Xiulin Wan, Yang Zhou, Baolei Jia, Shi Huang, Renyou Gan, Tao Wen, Tong Chen, Xia Chen, Xiaofang Li, Yong‐Xin Liu   +24 more
wiley   +1 more source

Genomic Analysis Reveals the Genetic Determinants Associated With Antibiotic Resistance in the Zoonotic Pathogen Campylobacter spp. Distributed Globally

Frontiers in Microbiology, 2020
The genus Campylobacter groups 32 Gram-negative bacteria species, several being zoonotic pathogens and a major cause of human gastroenteritis worldwide. Antibiotic resistant Campylobacter is considered by the World Health Organization as a high priority ...
Daniel Rivera-Mendoza, Irma Martínez-Flores, Rosa I. Santamaría, Luis Lozano, Víctor H. Bustamante, Deyanira Pérez-Morales   +5 more
doaj   +1 more source

Regional Differences in Presence of Shiga toxin-producing Escherichia coli Virulence-Associated Genes in the Environment in the North West and East Anglian regions of England [PDF]

, 2020
Shiga toxin-producing Escherichia coli is carried in the intestine of ruminant animals, and outbreaks have occurred after contact with ruminant animals or their environment.
Hunter, Paul R, Jones, Natalia, Kintz, Erica, Lake, Iain R, O'Brien, Sarah J, van der Es, Mike, Williams, Nicola J   +6 more
core   +1 more source

T‐2 Toxin Exploits Gut‐Derived Staphylococcus Saprophyticus to Disrupt Hepatic Macrophage Homeostasis

Advanced Science, EarlyView.
T‐2 toxin promotes the proliferation of intestinal S. saprophyticus and facilitates its translocation to the liver in piglets and mice. The translocated bacteria trigger autophagy in Kupffer cells and recruit monocytes to the liver through the nucleotide‐binding oligomerization domain 2 (NOD2) signaling pathway, alongside the M1 polarization of hepatic
Yuanyuan Zhu, Liu Xu, Fangrui Guo, Jianyu Qu, Xiangyan Liu, Qiurong Xu, Jie Sheng, Jiangping Wang, Xiaohong Xie, Ruimin Ren, Chuan Zhou, Sisi Yan, Shuiping Liu, Zhihang Yuan, Rongfang Li, Jing Wu, Jine Yi, Yulong Yin, Lixin Wen, Ji Wang   +19 more
wiley   +1 more source

Detection of mecC-Methicillin-resistant Staphylococcus aureus isolates in river water : a potential role for water in the environmental dissemination [PDF]

, 2014
Methicillin-resistant Staphylococcus aureus (MRSA) is a public health concern due to limited treatment options. The recent description of a mecA homologue, mecC in human and cattle, led to studies to detect this new variant in human and other animal ...
Concepcion Porrero, M., Diez-Guerrier, Alberto, Dominguez, Lucas, Domínguez Rodríguez, Lucas, Domínguez, Lucas, Díez-Guerrier, Alberto, Fernández-Garayzábal, José Francisco, Francisco Fernandez-Garayzabal, Jose, Harrison, Ewan, Harrison, Ewan M, Holmes, Mark A., Paterson, Gavin K., Porrero, M. Concepción   +12 more
core   +1 more source

Distinct Phage‐Encoded Enzymes for Substitution of Deoxythymidine by Deoxyuridine in Phage Genomes

Advanced Science, EarlyView.
Distinct enzymes including dCTP deaminases (Dcds), dTMP phosphatases (Dtms), and dTTP pyrophosphatases (Dtt) are found to be responsible for dU‐DNA biosynthesis in the phages PBS1, DSS3_VP1, and PhiR1‐37. Both PhiR1‐37‐derived and synthetic dU‐DNA are resistant to cleavage by restriction enzymes and Cas12a nuclease targeting dT‐containing sites.
Yating Li, Jason Tan, Yanqin Tu, Jingnan Wu, Zaifang Zhang, Yifeng Wei, Xinan Jiao, Yan Zhou   +7 more
wiley   +1 more source

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

Annals of Neurology, EarlyView.
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich, Martin Brüne, John S. Allen, Nicole Bender, Emiliano Bruner, Jean‐Pierre Changeux, Corrado Cali, Olga Dolgova, Anne Grünewald, Geneviève Konopka, Peng Jin, Roger Lemon, Gilberto Levy, Pierre Magistretti, Markus J. Rantala, Kathleen S. Rockland, Roger Sullivan, Annie Swanepoel, Toshiki Uchihara, Katrin Amunts, Christopher G. Goetz   +20 more
wiley   +1 more source