Zoonoses and Public Health, Volume 72, Issue 3, Page 324-329, May 2025.ABSTRACT Background Leptospirosis is a widespread zoonosis caused by bacteria in the genus Leptospira. Basic epidemiological information is crucial to mitigating disease risk but is lacking for leptospirosis; notably, the hosts responsible for maintaining Leptospira remain largely unknown.
Florence Ayral +4 more
wiley +1 more source
Understanding zoonotic pathogens and risk factors from wildlife in Southeast Asia: a systematic literature review. [PDF]
Vet QNguyen HTT +12 more
europepmc +1 more source
Considering the Risks and Costs of Solid Organ Xenotransplantation
Advanced Biology, Volume 9, Issue 4, April 2025.This perspective discusses the rationale, risks, and costs of whole‐organ xenotransplantation. It considers alternative strategies to obviate the demand for transplants and optimize allotransplantation systems and practices that do not impose xenotransplantation's harms and risks, and whether they are the most ethical and effective means to increase ...
Catharine E. Krebs +5 more
wiley +1 more source
Editorial: Pathogens at the interface of animals in close contact with humans: risks and benefits, with special regard to immunosuppressed people. [PDF]
Front Vet SciJelocnik M, Ferreira Neto JS, Natale A.
europepmc +1 more source
Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.This research highlights a novel application of protein nanoparticles to effectively modulate the strength, breadth, and bias of an immune response against influenza virus. Nanoparticles precisely co‐delivering antigen (H5) and multiple adjuvants (CpG and FliCc) present a way to improve and direct prophylactic immune responses which can be applicable ...
Aaron Ramirez +6 more
wiley +1 more source
Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon
Advanced Therapeutics, Volume 8, Issue 4, April 2025.Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap +10 more
wiley +1 more source
Zoonotic infections in semi-domesticated eurasian tundra reindeer (Rangifer tarandus tarandus) in Fennoscandia - a review. [PDF]
One Health OutlookTryland M, Buhler KJ.
europepmc +1 more source
Advanced Science, Volume 12, Issue 15, April 17, 2025.This work identifies a potent, non‐membrane active, and non‐toxic AMP termed GN1, which substantially resensitizes MRSA to multiple β‐lactam antibiotics at low concentrations. GN1 functions by suppressing MRSA‐associated resistance determinants, including penicillin‐binding protein 2a (PBP2a) and β‐lactamase.
Jingru Shi +6 more
wiley +1 more source
Navigating the Interconnected Web of Health: A Comprehensive Review of the One Health Paradigm and Its Implications for Disease Management. [PDF]
Yonsei Med JHernandez A, Lee J, Kang H.
europepmc +1 more source
Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development
ChemBioChem, Volume 26, Issue 7, April 1, 2025.Pyrimidine biosynthesis is a pivotal process shared by both eukaryotes and prokaryotes. This review examines the applications and advantages of a series of inhibitors specifically designed to target aspartate transcarbamylase within the de novo biosynthetic pathway of the malarial parasite.
Siyao Chen +8 more
wiley +1 more source