Results 21 to 30 of about 111,803 (260)

Evaluation of the impact of shigellosis exclusion policies in childcare settings upon detection of a shigellosis outbreak

BMC Infectious Diseases, 2019
Background In the event of a shigellosis outbreak in a childcare setting, exclusion policies are typically applied to afflicted children to limit shigellosis transmission. However, there is scarce evidence of their impact.
Cristina Carias, Eduardo A. Undurraga, Jacqueline Hurd, Emily B. Kahn, Martin I. Meltzer, Anna Bowen   +5 more
doaj   +1 more source

Comparison Of Bacillus anthracis Prepared Used Antigens As ‎Diagnostic kit Of Anthrax In Laboratoy Animals.‎

The Iraqi Journal of Veterinary Medicine, 2007
   This study was concerned on the preparation of several antigens on different types of culture media like brain heart infusion, tryptic soy agar and broth.
Al- Jebouri A.J. ‎, Al- Khatib G.M.‎   +1 more
doaj   +1 more source

Potential for broad-scale transmission of Ebola virus disease during the West Africa crisis: lessons for the Global Health security agenda

Infectious Diseases of Poverty, 2017
Background The 2014–2016 Ebola crisis in West Africa had approximately eight times as many reported deaths as the sum of all previous Ebola outbreaks.
Eduardo A. Undurraga, Cristina Carias, Martin I. Meltzer, Emily B. Kahn   +3 more
doaj   +1 more source

Vaccination and risk of lone atrial fibrillation in the active component United States military

Human Vaccines & Immunotherapeutics, 2019
Purpose: To evaluate the hypothesis that receipt of anthrax vaccine adsorbed (AVA) increases the risk of atrial fibrillation in the absence of identifiable underlying risk factors or structural heart disease (lone atrial fibrillation).
Michael M. McNeil, Susan K. Duderstadt, Jennifer F. Sabatier, Gina G. Ma, Jonathan Duffy   +4 more
doaj   +1 more source

Aetiological, seasonal and antibiotic susceptibility patterns of diarrhoeal diseases in Bhutan (2016–2022): a retrospective study of surveillance data

BMJ Open
Objectives This study aimed to identify the aetiological spectrum, seasonal distribution and antimicrobial resistance patterns of diarrhoeal diseases in Bhutan.Study design and setting The study used a cross-sectional, retrospective analysis of secondary
Sangay Dorji, Kinley Gyem, Sonam Pelden, Dorji Tshering, Kinley Penjor, Rinzin Wangchuk, Jigme Tenzin, Birdi Lal Phuyel   +7 more
doaj   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Patterns of genomic deletions in monkeypox virus during the 2022 outbreak in the United States

Nature Communications
Poxviruses have a low overall rate of point mutations but are known to exhibit genomic duplications and deletions that can influence viral evolution.
Crystal M. Gigante, Daisy McGrath, Sophia Sukkestad, Hui Zhao, Mengfei Peng, Jade Takakuwa, Kimberly Wilkins, Vaughn Wicker, Audrey Matheny, Theodora Khan, Whitni B. Davidson, Mili Sheth, Alex Burgin, Julie Hand, Gillian Richardson, Danielle Haydel, Mark Burroughs, Jasmine Padilla, Justin S. Lee, Dhwani Batra, Ethan E. Hetrick, Dakota T. Howard, Kyle O’Connell, Jessica L. Rowell, Shatavia Morrison, Sarah Gillani, Michelle Lee, Anil Mangla, David Blythe, Robert Myers, Lynsey Kovar, Matthew H. Seabolt, Michael R. Weigand, Panayampalli S. Satheshkumar, Andrea M. McCollum, Christina L. Hutson, Yu Li   +36 more
doaj   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

Risk of Nipah virus transmission through date palm sap trade in Bangladesh: a qualitative ethnographic study

One Health Outlook
Background Nipah virus is an emerging zoonotic pathogen with pandemic potential, primarily transmitted through the consumption of raw date palm sap contaminated with bat excretions.
A. K. M. Dawlat Khan, Ariful Islam, Sarah Munro, Pronesh Dutta, Md. Arif Khan, Monjurul Islam, Nabila Nujhat Chowdhury, Sharmin Sultana, Maryska Kaczmarek, Shusmita Dutta Choudhury, Tahmina Shirin, Jonathan H. Epstein   +11 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source