Results 61 to 70 of about 111,803 (260)

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

Brain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye, Fei Peng, Chao Pan, Ping Zhang, Xuewei Xie, Zixiao Li, Yingxin Tang, Danyang Chen, Yuanwei Li, Jiawen Wu, Zao Han, Qing Dai, Quansheng Gu, Jizong Zhao, Zhouping Tang   +14 more
wiley   +1 more source

Beyond birds: rethinking bird‐centered pathogen models in light of insect migration

Ecography, EarlyView.
Migration redistributes biomass, nutrients, and pathogens across ecosystems. For decades, migratory birds have been treated as the default long‐distance pathogen vectors, shaping both conceptual frameworks and empirical models of disease ecology.
Virginia Morandini
wiley   +1 more source

‘SiteTool': a ‘Shiny' application for field site selection and evaluation

Ecography, EarlyView.
Field studies are fundamental to ecological research, yet many studies rely on unspecified or convenience‐based methods for site selection, potentially introducing bias that can compromise research results. Remote‐sensing data provides a quantitative way to evaluate potential sites without expensive pilot visits; however, interacting with spatial data ...
Natalie Imirzian, Artur Trebski, Emilia Johnson, Madison Hewitson, David Simons, Christina Harden, Sagan Friant, David Redding   +7 more
wiley   +1 more source

Real‐World Utilization Patterns of Toxoplasmosis Diagnostic Testing in Korea: A Large‐Scale Laboratory‐Based Study

Journal of Clinical Laboratory Analysis, EarlyView.
We conducted a large retrospective analysis of real‐world Toxoplasma gondii IgG, IgM, and PCR testing performed at a nationwide referral laboratory in Korea to characterize diagnostic utilization patterns and test performance in routine clinical practice.
Rihwa Choi, Sang Gon Lee
wiley   +1 more source

Quality Control Assessment of Canadian Laboratories Testing for Lyme Disease

Canadian Journal of Infectious Diseases, 1991
In June 1990 a quality control assessment was undertaken of Canadian public health laboratories testing for antibodies to Borrelia burgdorferi, the etiological agent of Lyme disease.
Harvey Artsob, Maxwell Garvie
doaj   +1 more source

Excess death estimates compared with state-reported and observed COVID-19 deaths, New Jersey and the United States, 2020–2022

Frontiers in Public Health
Deaths associated with COVID-19 in the United States are currently estimated to be over 1.2 million, but the true burden of mortality due to the SARS-CoV-2 virus is unknown.
Diana Reichbind, Lemlem Mehari, Mojisola Ojo, Nagla Bayoumi, Edward Lifshitz   +4 more
doaj   +1 more source

Bayesian model averaging: improved variable selection for matched case-control studies

Epidemiology, Biostatistics and Public Health, 2019
Background: The problem of variable selection for risk factor modeling is an ongoing challenge in statistical practice. Classical methods that select one subset of exploratory risk factors dominate the medical research field.
Yi Mu, Isaac See MD, Jonathan R. Edwards MSc   +2 more
doaj   +1 more source

Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering

Medicinal Research Reviews, EarlyView.
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo, Shinwon Kang, Jae Eun Yang, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source