Results 41 to 50 of about 1,858,564 (306)

Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs [PDF]

, 2012
Hepatitis E virus (HEV) is an important but extremely understudied human pathogen. Genotypes 1 and 2 are restricted to humans, whereas genotypes 3 and 4 are zoonotic, infecting both humans and pigs.
Meng, Xiang-Jin, Feagins, Alicia R, Huang, Yao-Wei, Córdoba, Laura, Dryman, Barbara A, Opriessnig, Tanja, Cossaboom, Caitlin M   +6 more
core   +1 more source

casanchez/rodenticide-rat-infection: Rodenticide and rat infection analysis v1.0.0

, 2021
Code to generate results and figures for Murray & Sánchez. Urban rat exposure to anticoagulant rodenticides and zoonotic infection risk.
Cecilia A. Sanchez
core   +1 more source

Prevalence of zoonotic helminths in Italian house dogs [PDF]

, 2018
Introduction: Dogs may act as potential sources of zoonotic parasites, e.g. intestinal helminths like Toxocara spp., Ancylostoma spp., Echinococcus spp.
Simonato, Giulia, Giulia Simonato, Traversa, Donato, La Torre, Francesco, Cassini, Rudi, Donato Traversa, Frangipane di Regalbono, Antonio, Rudi Cassini, Di Cesare, Angela, Antonio Frangipane di Regalbono, Francesco La Torre, Angela Di Cesare, Traversa D., La Torre F., Cassini R., Simonato G., Di Regalbono A. F., Di Cesare A.   +17 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. [PDF]

, 2015
Streptococcus suis causes disease in pigs worldwide and is increasingly implicated in zoonotic disease in East and South-East Asia. To understand the genetic basis of disease in S.
Schultsz, C, Langford, P.R., Maglennon, Gareth A, Campbell, J., Wang, J., Chieu, T.T.B., Tran, TBC, Wren, B.W., Hoa, N.T., Tucker, Alexander W, Corander, Jukka, Corander, J., Ngo Thi, H, Schultsz, Constance, Valimaki, N, Wren, BW, Schultsz, C., Farrar, Jeremy, Holden, M T G, Wren, B W, Baker, S., Peters, Sarah E., Wang, Jinhong, Jombart, T., Maskell, DJ, Cuccui, Jon, Vehkala, Minna, Chaudhuri, RR, Chieu, TTB, Campbell, James, Rycroft, Andrew N, Campbell, J, Weinert, Lucy A, Wren, Brendan W, BRaDP1T Consortium, Chaudhuri, R R, Wang, J, Chaudhuri, Roy R, Terra, Vanessa, Chieu, Tran Thi Bich, Baig, Abiyad, Rycroft, A N, Nguyen, VVC, Howell, Kate J, Parkhill, Julian, Maskell, D J, Bentley, S D, Chaudhuri, R.R., Chau, N.V.V., Howell, Kate J., Baker, Stephen, Valimaki, N., Jombart, Thibaut, Baker, S, Ngo Thi Hoa, Tucker, AW, Weinert, LA, Ngo, TH, Baig, A., Peters, S.E., Rycroft, A.N., Tucker, A.W., Holden, Matthew T G, Tucker, Alexander W., Chau, Nguyen Van Vinh, Howell, K.J., Peters, SE, Vehkala, M, Parkhill, J, Matthews, Dominic, Vehkala, M., Peters, S E, Bentley, Stephen D, Harris, D., Langford, PR, Chaudhuri, Roy R., Bentley, Stephen D., Holden, Matthew T. G., Tran Thi Bich Chieu, Nguyen, Van Vinh Chau, Baig, A, Farrar, J, Corander, J, Li, Yanwen, Langford, Paul R, Holden, M.T.G., Weinert, Lucy A., Bosse, Janine T, Jombart, T, Välimäki, Niko, Bentley, S.D., Holden, MTG, Tran, Thi Bich Chieu, Maskell, Duncan J, Hoa, NT, Rycroft, Andrew N., Rycroft, AN, Tucker, A W, Maskell, Duncan J., Langford, Paul R., Bentley, SD, Peters, Sarah E, Holden, Matthew TG, Howell, K J, Farrar, J., Parkhill, J., Wren, Brendan W., Weinert, L.A., Nguyen Van Vinh Chau, Maskell, D.J., BRaDP1T Consortium,, Hoa, Ngo Thi, Van Vinh Chau, Nguyen, Weinert, L A, Howell, KJ, Nguyen Van Vinh, C, Harris, D, Langford, P R, Van Vinh Chau, N, Harris, David, Tran Thi Bich, C, Vaelimaeki, N, Holden, Matthew T G; id_orcid   +122 more
core   +6 more sources

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Antibody‐Precomplexed Hemagglutinin Constructs Multivalently Bind Sialylated Glycan Receptors with Variable Valencies

Advanced Materials Interfaces, EarlyView.
Hemagglutinin precomplexation with antibodies (Abs) results in broad valency distributions, though it increases the total avidity from mM to nM to high nM. The valency distribution and the orientation of multivalent HA‐Ab complexes determine the extent of binding to different types of assays, whether the receptors are displayed in 2D or 3D.
Daniel Y. E. L. Tambuwun, María Ríos Carrasco, Elif Uslu, Geert‐Jan P. H. Boons, Nadia J. Mokiem, Albert J. R. Heck, Victor C. Yin, Robert P. de Vries, Jurriaan Huskens   +8 more
wiley   +1 more source

A Case of Endocarditis due to Coxiella burnetii

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2022
A 36-year-old male patient, who was an agricultural farmer and had a diagnosis of bicuspid aortic valve and coarctation, was admitted with symptoms of fever, fatigue, and shortness of breath that lasted for a month, in March 2017.
Selda AYDIN, Okan DERİN, Mesut YILMAZ
doaj   +1 more source

Horses and the risk of zoonotic infections

Veterinary Clinics of North America: Equine Practice, 2004
Infectious agents are insidious, often changing to adapt to host defenses or treatment advances. Because these challenges will continue, the need to apply standard and transmission-based precautions is important not only in the human hospital setting but in the veterinary clinic setting.
Bender, Jeff B., Tsukayama, Dean T.
openaire   +2 more sources

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source