Results 71 to 80 of about 114,939 (262)

Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins

Biotechnology Progress, EarlyView.
Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann, Augustine Duffy, Alex Wee, Noah Anderson, Jackson Terrell, Yoshihiro Kawaoka, Ravi S. Kane   +6 more
wiley   +1 more source

Risk Evaluation and Mitigation Strategies for Newly Detected Mysterious Dinga Dinga Virus Infection in Africa: A Narrative Review

Health Science Reports
Background and Aims The Dinga Dinga Virus (DDV) has emerged as a mysterious disease gripping women in Uganda, raising alarm due to its unusual and distressing “dancing” like symptoms.
Sabrina Sharmin, Salsabil Islam, Md. Aminul Haque, Md. Rabiul Islam   +3 more
doaj   +1 more source

From Surgical Innovation to Population Impact: Robot‐Assisted Radical Prostatectomy and the Evolution of Surgical Public Health in Brazil's Unified Health System

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Brazil's Unified Health System (Sistema Único de Saúde, SUS) represents one of the world's largest universal health systems and provides a unique real‐world platform for integrating prevention, diagnosis, treatment, and survivorship across the cancer continuum.
Leonardo Oliveira Reis
wiley   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Radical Listening as a Governance Innovation: Integrating Planetary Health and Community‐Led Forest Conservation in Indonesia

Environmental Policy and Governance, EarlyView.
ABSTRACT While REDD+ prioritizes carbon sequestration, its narrow focus often overlooks forest‐health linkages critical to community well‐being. This paper examines the holistic model of Health in Harmony (HIH) and Alam Sehat Lestari (ASRI), which integrates forest conservation with healthcare through radical listening—a decolonial community engagement
Angie Hsu, Nur Febriani, Luce Alvafritz, Firdani Asri   +3 more
wiley   +1 more source

Potential for conflict between urban coyotes and people experiencing unsheltered homelessness

Frontiers in Ecology and the Environment, EarlyView.
Across North America, both unsheltered homelessness and human–coyote (Canis latrans) conflict are increasing, but the relationship between these phenomena has not been thoroughly explored. We synthesize literature‐based evidence with anecdotal observations that occurred during a 15‐year study of coyotes in Edmonton, Canada, to describe three likely ...
Sage Raymond, Jeff Rose, Colleen Cassady St Clair   +2 more
wiley   +1 more source

Zoonotic aspects of infections with noroviruses and sapoviruses

Veterinary Microbiology, 2010
The close genetic relationship of noroviruses and sapoviruses found in animals and humans has raised the question whether these viruses have a zoonotic potential. Transmission from animals to humans and vice versa would have far-reaching consequences for epidemiology and food safety.
Bank-Wolf, Barbara Regina, König, Matthias, Thiel, Heinz-Jürgen   +2 more
openaire   +2 more sources

Development and External Validation of an Efficient Deep Learning Model for Lesion Segmentation and Subtyping of Hepatic Echinococcosis in Ultrasound Imaging

Health Care Science, EarlyView.
We developed a lightweight deep learning framework that integrates frequency‐ and spatial‐domain ultrasound features with segmentation‐assisted classification for hepatic echinococcosis diagnosis. The model outperformed existing state‐of‐the‐art methods in both accuracy and inference speed while requiring substantially fewer computational resources ...
Zhu He, Jiajun Qiu, Chenlin Du, Jin Yin, Xuhui Zhang, Yelei Ren, Yifei Wang, Lamu Suolang, Chunyang Li, Zongjiu Zhang, Diming Cai, Qicheng Lao   +11 more
wiley   +1 more source

The Impact of Human Activities on Zoonotic Infection Transmissions. [PDF]

Animals (Basel), 2023
Esposito MM, Turku S, Lehrfield L, Shoman A.   +3 more
europepmc   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source