Results 51 to 60 of about 13,841 (201)
Advances in understanding the mechanism of action of adult vaccines
The Journal of Clinical Investigation, 2023 The occurrence of herpes zoster (HZ) correlates with declining memory T cells that had responded to earlier infection with varicella-zoster virus (VZV).
Anthony L. Cunningham +2 more
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When, which and how to switch: Navigating JAK inhibitors in myelofibrosis
British Journal of Haematology, EarlyView.Navigating choice of JAK inhibitor (JAKi) therapy for patients with myelofibrosis who are JAKi‐naïve and for those who have previously been treated with a JAKi.
Jennifer O'Sullivan +2 more
wiley +1 more source
Viruses, 2023 Herpes zoster (HZ) is a disease caused by the reactivation of latent varicella-zoster virus (VZV). The subunit vaccine, Shingrix®, and live attenuated vaccine, Zostavax®, could be used as an HZ vaccine that prevents HZ from being developed due to the ...
Yanpeng Zheng +8 more
doaj +1 more source
Review of Varicella zoster virus : from epidemiology to prevention [PDF]
, 2008 The Varicella zoster virus is a human pathogen which causes Varicella after primary infection and herpes zoster after secondary reactivation. Both disease manifestations can occur at any age; however, Varicella is seen more commonly in children whilst ...
Pace, David
core
Using the nonhuman primate model of HCMV to guide vaccine development. [PDF]
, 2014 The natural history of human cytomegalovirus (HCMV) is inextricably associated with mucosal surfaces. The vast preponderance of primary infections occur following mucosal exposure to infectious virions, and the high seroprevalence of HCMV throughout the ...
Barry, Peter A, Deere, Jesse D
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The FEBS Journal, EarlyView.Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner +13 more
wiley +1 more source
Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years
Journal of the European Academy of Dermatology and Venereology, EarlyView.The current study found no evidence of cumulative increased safety risks with upadacitinib 15 or 30 mg for up to 6 years and over 9000 patient‐years of safety data in adults and adolescents. There were low rates of adjudicated major adverse cardiovascular events, adjudicated thromboembolic events and malignancies. Abstract Background Atopic dermatitis (
Christopher G. Bunick +13 more
wiley +1 more source
A Dose-Response Study of a Live Attenuated Varicella-Zoster Virus (Oka Strain) Vaccine Administered to Adults 55 Years of Age and Older [PDF]
, 2017 Decreased cell-mediated immune (CMI) response to varicella-zoster virus (VZV) is correlated with an increased risk of reactivation of latent virus from dorsal root sites, leading to herpes zoster.
Bailleux, Fabrice +5 more
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The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design
Journal of the American Geriatrics Society, EarlyView.ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui +11 more
wiley +1 more source
Varicella zoster virus vaccines: an update
ImmunoTargets and Therapy, 2019 Giovanni Gabutti,1 Niccolò Bolognesi,2 Federica Sandri,2 Caterina Florescu,2 Armando Stefanati11Department of Medical Sciences, University of Ferrara, Ferrara, Italy; 2Postgraduate School of Hygiene and Preventive Medicine, University of Ferrara ...
Gabutti G +4 more
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