Results 71 to 80 of about 13,841 (201)

Herpes Zoster in Children and Adolescents: Case Series Of 8 Patients

open access: yesNational Journal of Community Medicine, 2013
Herpes zoster can occur at any age but is rare in childhood and adolescents. Zoster can occur at any time after primary varicella infection or varicella vaccination. Recent studies have shown its increasing incidence in children.
Pragya A Nair, Pankil H Patel
doaj  

Varicella and Herpes zoster vaccines: from live attenuated vaccines to genetically engineered products

open access: yesБиопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. Varicella zoster virus remains a serious threat to public health and is a sig­nificant burden on the health system due to treatment costs. Vaccination coverage against varicella zoster (VZ) and herpes zoster (HZ) remains low for a number of
A. V. Zotova, O. A. Svitich
doaj   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

open access: yesJournal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron   +3 more
wiley   +1 more source

Accelerate the Highly Efficient Development of mRNA Vaccines Through Advanced Computational Methods

open access: yesMedComm, Volume 7, Issue 2, February 2026.
This review explores the recent advancements in applying computational methods to optimize mRNA vaccines, with a primary focus on improvements in sequence design and delivery systems. ABSTRACT mRNA medicine is an emerging therapeutic approach that utilizes messenger RNA to synthesize functional proteins directly within target cells.
Ruichu Gu   +5 more
wiley   +1 more source

Development of Novel Immunoassays for Varicella Zoster Virus (VZV) Vaccine and Preliminary Study on Functional Domain of ORF7 protein [PDF]

open access: yes, 2016
水痘-带状疱疹病毒(Varicella-ZosterVirus,VZV)是水痘和带状疱疹的病原体。VZV具有高度传染性,初次感染可引发水痘,并可潜伏于患者背根神经节,在年老或免疫力低下时可能激活导致带状疱疹,具有严重的危害性。接种疫苗是预防VZV感染的有效方式,但目前使用的VZV减毒活疫苗株v-Oka仍具有感染和潜伏人神经系统的能力,安全隐患不容忽视,因此,亟需研制更为安全有效的新型疫苗。高效、精确的免疫分析技术体系是研制新型疫苗的重要基础。VZV是一种基因组约125Kb,拥有70个ORF ...
刘剑
core  

A systematic review and meta-analysis of risk factors for postherpetic neuralgia. [PDF]

open access: yes, 2015
Patients with herpes zoster can develop persistent pain after rash healing, a complication known as postherpetic neuralgia. By preventing zoster through vaccination, the risk of this common complication is reduced.
Bhaskaran, Krishnan   +6 more
core   +1 more source

Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions

open access: yesAllergy, Volume 81, Issue 2, Page 326-344, February 2026.
ABSTRACT Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. The clinical presentation of AD is heterogeneous and is characterized by a relapsing and remitting course. Most patients suffer from mild AD while approximately 5% to 20% experience severe disease activity, which often requires systemic treatment ...
Marjolein S. de Bruin‐Weller   +9 more
wiley   +1 more source

Vaccines for preventing herpes zoster in older adults

open access: yesSão Paulo Medical Journal
BACKGROUND:Herpes zoster or, as it is commonly called, 'shingles' is a neurocutaneous disease characterised by the reactivation of varicella zoster virus (VZV), the virus that causes chickenpox, which is latent in the dorsal spinal ganglia when immunity ...
Ana M. Z. Gagliardi   +3 more
doaj   +1 more source

Fatal disseminated varicella zoster infection following zoster vaccination in an immunocompromised patient [PDF]

open access: yes, 2016
A 79-year-old man with chronic lymphocytic leukaemia presented with fever and a widespread vesicular rash on 19 November 2014. The patient had not been under immunosuppressive regime for 6 months.
Breuer, J   +5 more
core   +1 more source

Vaccination Recommendations in Patients With Atopic Dermatitis Treated With JAK Inhibitors

open access: yesInternational Journal of Dermatology, Volume 65, Issue 2, Page 230-237, February 2026.
Inmunization and Screening Protocol for the Safe Initiation of JAK Inhibitors. ABSTRACT Atopic dermatitis therapy has undergone a revolutionary change with the introduction of Janus kinase (JAK) inhibitors. Despite their general safety profile, these immunomodulatory drugs require special precautions with respect to infection risk and vaccine ...
Mariano Ara‐Martín   +5 more
wiley   +1 more source

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