Results 141 to 150 of about 161,623 (285)

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

open access: yesAdvanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang   +12 more
wiley   +1 more source

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

open access: yesAdvanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu   +8 more
wiley   +1 more source

Type‐II Dirac Fermions in Monolayer In2O: Interplay of Magnetotransport, Spin Hall Effect, and Superconductivity

open access: yesAdvanced Science, EarlyView.
First‐principles calculations reveal that monolayer In2O${\rm In}_2{\rm O}$ hosts type‐II Dirac fermions near the Fermi level, which split into Weyl points under spin‐orbit coupling. The material exhibits negative and giant magnetoresistance, a pronounced spin Hall effect, and phonon‐mediated superconductivity at 1.5 K, establishing it as a unique ...
Qing‐Bo Liu   +6 more
wiley   +1 more source

Novel Al-Cu-Mn-Zr-Sc Compositions Exhibiting Increased Mechanical Performance after a High-Temperature Thermal Exposure

open access: yes, 2020
Novel Al-Cu-Mn-Zr-Sc Compositions Exhibiting Increased Mechanical Performance after a High-Temperature Thermal ...
Thomas Dorin (13067616)   +3 more
core  

Unifying Composition and Process Design: A Heterogeneous Graph Neural Network for Discovering High‐Performance Cu Alloys

open access: yesAdvanced Science, EarlyView.
By overcoming the fixed‐path limitations of conventional machine learning, a heterogeneous graph neural network fundamentally reconstructs material data representation. Integrating variable processing sequences with intrinsic elemental features, this framework enables exploratory optimization across high‐dimensional spaces.
Jie Yin   +12 more
wiley   +1 more source

Treatment of patients with chronic thrombo­embolic pulmonary hypertension: focus on riociguat

open access: yesTherapeutics and Clinical Risk Management, 2016
Zachary R Smith,1 Charles T Makowski,1 Rana L Awdish2 1Department of Pharmacy Services, 2Pulmonary and Critical Care Medicine Division, Henry Ford Hospital, Detroit, MI, USA Abstract: Chronic thromboembolic pulmonary hypertension (CTEPH) is a disease ...
Smith ZR, Makowski CT, Awdish RL
doaj  

Micro-segregation and precipitates in as-solidified Al-Sc-Zr-(Mg)-(Si)-(Cu) alloys

open access: yes, 2019
© 2019 Elsevier Inc. In this work, we investigate the as-cast microstructure of three model alloys, an Al-Sc-Zr, an Al-Mg-Si-Sc-Zr and an Al-Mg-Si-Cu-Sc-Zr alloy.
Thomas Dorin (13067616)   +3 more
core  

Engineering of Crystal and Domain Structures in Epitaxial Y:HfO2 Thin Films by YSZ Substrate Miscut

open access: yesAdvanced Science, EarlyView.
We investigate how YSZ substrate miscut influences crystal structure and domain formation in epitaxial Y‐doped HfO2 thin films. Using magnetron sputtering, high‐resolution X‐ray diffraction, atomic‐resolution scanning transmission electron microscopy, and first‐principles calculations, we systematically examine the characteristics of thickness‐ and ...
Jun Young Lee   +12 more
wiley   +1 more source

Supplementary information files for "Recommended solutions for the disinfection of Ti-Zr-cu-pd bulk metallic glasses"

open access: yes
Supplementary files for article "Recommended solutions for the disinfection of Ti-Zr-cu-pd bulk metallic glasses"Disinfection of medical devices is crucial to patient safety. Notably, an incorrect selection of disinfectant can damage the material surface
Janelle Tarum (17586378)   +3 more
core   +1 more source

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