Results 231 to 240 of about 161,623 (285)

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

Effect of group IV content on elastic and defect properties of NbTiZr refractory medium-entropy alloys. [PDF]

Sci Technol Adv Mater
Tsuru T, Lobzenko I, Han S, Inui H.
europepmc   +1 more source

Ablation‐Immune Thermal Armor Via Microstructural‐Compatibility Design for Extreme Thermal Conditions

Advanced Science, EarlyView.
This study unveils a microstructural‐compatibility design strategy that integrates reactive melt infiltration with plasma spraying to fabricate carbon fiber‐reinforced ZrC‐SiC composites. The deliberate incorporation of SiC into the ZrC coating releases heat accumulation, suppresses detrimental lamellar ZrO2 formation, and reduces residual stress. This
Hongkang Ou, Lingxiang Guo, Bing Liu, Ziyi Yi, Yuyu Zhang, Jia Sun, Qiangang Fu   +6 more
wiley   +1 more source

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

Advanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu, Lesong Wei, Jianmin Wang, Yuanpeng Xiong, Ruochi Zhang, Yu Wang, Chao Zha, Qiangcheng Zeng, Xin Gao   +8 more
wiley   +1 more source

Overcoming the Biomechanical Limitations of Titanium-Zirconia Dental Implants: Rationale for a Novel Ti-PEEK-Zr Tri-Layered Concept. [PDF]

J Funct Biomater
Vacaru MC, Munteanu C, Lupu FC, Deleu G, Volocaru II, Earar K.   +5 more
europepmc   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Evaluation of the Influence of Tantalum on the Microstructural, Mechanical and Electrochemical Properties of Ti-Mo-Zr-xTa Alloys for Use in Biomedical Devices. [PDF]

J Funct Biomater
Jimenez-Marcos C, Mirza-Rosca JC, Baltatu MS, Vizureanu P.   +3 more
europepmc   +1 more source

Highly efficient MOF-808/polyethersulfone mixed matrix membranes for methyl orange filtration. [PDF]

RSC Adv
Hu XJ, Li QQ, Lin LJ, Huang XH, Ying SM.
europepmc   +1 more source

Mechanistic Insights into Hf(IV)/Zr(IV) Extraction by D2EHPA in Sulfate Media: A DFT Study Supported by Experiments with Industrial Sulfate Liquors. [PDF]

ACS Omega
Novaes PAA, Mingote RM, Morais CA, Bertoli AC, Duarte HA.   +4 more
europepmc   +1 more source