Results 211 to 220 of about 163,740 (287)

Cell Surface Expression and PET Imaging Establish DLL3 as a Clinically Actionable Target in Neuroblastoma. [PDF]

J Nucl Med
Aspromonte SM, Feinberg TY, Gavane S, Parker C, Cihan A, You D, Tendler SA, Alvarez-Perez J, Brosius S, Siddiquee A, Domenico D, Ibañez G, Stockfisch E, Bean JM, Cochrane AM, Bhanot U, Tickoo SK, Jungbluth A, Frosina D, Angelini P, Shukla N, Lyashchenko SK, Poirier JT, Schoder H, Rudin CM, Lewis JS, Curran KJ, Daniyan A, Dunphy MP, Glade Bender JL, Modak S, Dela Cruz FS, Kung AL.   +32 more
europepmc   +1 more source

Ablation‐Immune Thermal Armor Via Microstructural‐Compatibility Design for Extreme Thermal Conditions

Advanced Science, EarlyView.
This study unveils a microstructural‐compatibility design strategy that integrates reactive melt infiltration with plasma spraying to fabricate carbon fiber‐reinforced ZrC‐SiC composites. The deliberate incorporation of SiC into the ZrC coating releases heat accumulation, suppresses detrimental lamellar ZrO2 formation, and reduces residual stress. This
Hongkang Ou, Lingxiang Guo, Bing Liu, Ziyi Yi, Yuyu Zhang, Jia Sun, Qiangang Fu   +6 more
wiley   +1 more source

B7-H3 molecular imaging for the era of pan-cancer targeted therapy. [PDF]

Front Pharmacol
Liu B, Wang K, He K, Wang Y.
europepmc   +1 more source

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

Advanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu, Lesong Wei, Jianmin Wang, Yuanpeng Xiong, Ruochi Zhang, Yu Wang, Chao Zha, Qiangcheng Zeng, Xin Gao   +8 more
wiley   +1 more source

Biological performance enhancement of Ni-free Zr-based bulk metallic glass for dental implants via nitrogen plasma immersion ion implantation. [PDF]

J Dent Sci
Huang HM, Sun YS, Huang YL, Lin KY, Porntaveetus T, Osathanon T, Chen WC, Huang HH.   +7 more
europepmc   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Engineering Zr-W Mixed Oxide Heterojunctions from UiO-66-Type MOFs Templates: Bridging DFT and Mechanistic Insights into Organic Abatement. [PDF]

ACS Omega
Fotsop CG, Lieb A, Scheffler F.
europepmc   +1 more source

Nrsn1–Smarcc1 Coupling Regulates Neural Stem Cell Differentiation and Chronic‐phase Recovery After Ischemic Stroke

Advanced Science, EarlyView.
In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang, Chang Liu, Yuneng Zhou, Kaichen Zhao, Muyang Li, Bingcheng Cai, Ying Wang, Zhiyuan Yuan, Zhaoxin Liu, Zilong Yuan, Yao Xiao, Peiyang Zhou, Ke Shui, Wendai Bao, Min Zhang, Jun Qin, Jun Chen, Xin Yang, Zhiqiang Dong   +18 more
wiley   +1 more source

Radium-223 decreases PD-L1 expression in bone metastases: A study with [⁸⁹Zr]Zr-atezolizumab PET and immunohistological correlation. [PDF]

Eur J Nucl Med Mol Imaging
Ling SW, de Jong A, Gorris M, Segbers M, Graven L, van Driel M, van Leenders G, Isebia K, de Hooge ML, Hamberg P, Mehra N, van Brakel M, de Wit R, Debets R, de Vries E, Brabander T, de Vries J, van der Veldt A.   +17 more
europepmc   +1 more source