Results 31 to 40 of about 161,623 (285)

Evaluation of different 89Zr-labeled synthons for direct labeling and tracking of white blood cells and stem cells in healthy athymic mice

Scientific Reports, 2022
Cell based therapies are evolving as an effective new approach to treat various diseases. To understand the safety, efficacy, and mechanism of action of cell-based therapies, it is imperative to follow their biodistribution noninvasively.
Aditya Bansal, Shalini Sharma, Benedikt Klasen, Frank Rösch, Mukesh K. Pandey   +4 more
doaj   +1 more source

Interdiffusion in Zr-Mo/W Intermetallics

Applied Sciences, 2023
Intermetallic compounds or solid solutions can form between Zr and Mo/W, in which the multiphase of the diffusion may be influenced by each other. Interdiffusion kinetic data in such intermetallic systems are highly demanded for material design.
Kaihua Wang, Xingwei Liu, Tianyu Liu, Chuan He, Jinxu Liu   +4 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Synthesis and Structural Characterization of U-Zr-Nb Alloys

, 2017
U-xZr-yNb alloys with values of x varying from 32% to 50% (wt.%Zr) and y varying from 6% to 10% (wt.%Nb) were produced by the arc melting technique. The effect of the addiction of zirconium and niobium on the phase stabilization of γ-U, lattice parameter,
Flávio Francisco Ivashita (5222753), Fábio Rogério Longen (5222756), Ailton da Silva Ferreira (5222759), Reginaldo Barco (5222762), Andrea Paesano Júnior (5222747), Ricardo Augusto Mascarello Gotardo (5222750)   +5 more
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Stress Distribution on Bone Due to Dental Implant

Journal of Pharmacy and Bioallied Sciences
Background: The distribution of stress (DS) in the bone around dental implant (DI) during loading is associated with success. In contrast, upon loosening of DI because of high stress, leads to its failure.
Ajay Gaikwad, Lishoy W Rodrigues, Karuna Gajanan Pawashe, Praveen Gangadharappa, Amit Bajirao Jadhav, Shruti Dabi   +5 more
doaj   +1 more source

Hepta-Zr-Incorporated Polyoxometalate Assembly

, 2022
Driven by the synergistic-directing effect of the lacunary fragments, [B-α-GeW9O34]10– and [B-α-GeW11O39]8–, an unprecedented hepta-Zr-substituted polyoxometalate (POM) assembly K2Na6H10(Hpy)3[SbZr7O6(OH)4(B-α-GeW9O34)2(B-α-GeW11O39)2]·28H2O (1) was made
Guo-Yu Yang (1728175), Yu Wang (12152), Peng-Yun Zhang (12973897), Liao-Yuan Yao (1635193)   +3 more
core   +1 more source

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Complementing Engel Classification: Postoperative Scalp EEG as an Objective Indicator in SEEG‐Guided Radiofrequency Thermocoagulation—A Seizure‐Onset Pattern‐Based Stratified Analysis—

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) is a minimally invasive therapy for drug‐resistant focal epilepsy. However, the relationship between specific seizure‐onset patterns (SOPs), particularly low‐voltage fast activity (LVFA), and postoperative scalp EEG normalization remains inadequately ...
Yi‐qing Yang, Rui Zhang, Haiyan Ma, Lu Yang, Xuefeng Qu, Qiqi Chen, Yan Zhang   +6 more
wiley   +1 more source

Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo, Claudia Dosi, Stefano Parravicini, Riccardo Zanin, Marta Cheli, Eleonora Giacopuzzi Grigoli, Amalia Canciello, Francesca Andreetta, Riccardo Masson, Silvia Bonanno, Stefania Marcuzzo, Lorenzo Maggi   +11 more
wiley   +1 more source