Results 1 to 10 of about 16,136 (213)

Effective noninvasive zygosity determination by maternal plasma target region sequencing. [PDF]

PLoS ONE, 2013
BACKGROUND: Currently very few noninvasive molecular genetic approaches are available to determine zygosity for twin pregnancies in clinical laboratories.
Jing Zheng, Chenming Xu, Jing Guo, Yuan Wei, Huijuan Ge, Xuchao Li, Chunlei Zhang, Haojun Jiang, Ling Pan, Weiping Tang, Weiwei Xie, Hongyun Zhang, Yangyu Zhao, Fuman Jiang, Shengpei Chen, Wei Wang, Xun Xu, Fang Chen, Hefeng Huang, Hui Jiang   +19 more
doaj   +3 more sources

Predicting Zygosity based on physical similarity of twin pairs with the aid of machine learning methods [PDF]

BMC Medical Informatics and Decision Making
Background Given the importance of distinguishing identical and non-identical twins and the high cost of genetic testing, the ability to estimate zygosity using self-reported methods could be invaluable in reducing the costs of twin research.
Hamidreza Abtahi, Maryam Edalatifard, Marsa Gholamzadeh, Elmira Khakvatan   +3 more
doaj   +2 more sources

The gut mycobiome is shaped by interactions with the bacterial community in twins [PDF]

iScience
Summary: The human gut microbiome comprises bacteria, viruses, and fungi, yet the fungal component (mycobiome) remains poorly characterized. Here, we investigated gut fungal composition and fungal–bacterial interactions in healthy monozygotic and ...
Konrad Lehr, Ramiro Vilchez-Vargas, Jurgita Skieceviciene, Noam Mathias Hipler, Greta Gedgaudienė, Indre Gustaityte, Laimutis Kucinskas, Mindaugas Urba, Cosima Thon, Denny Schanze, Martin Zenker, Juozas Kupcinskas, Alexander Link   +12 more
doaj   +2 more sources

Ultrasound and SNP-based cell-free DNA zygosity testing in twin pregnancies

Journal of Maternal-Fetal and Neonatal Medicine
Introduction The importance of prenatal determination of chorionicity for the management of twin pregnancies is well recognized. However, research on the contribution of prenatal evaluation of zygosity to the management of twins is limited.
K Joseph Hurt, Eftichia Kontopoulos, Clark T Johnson   +2 more
exaly   +3 more sources

Rapid and precise genotyping of transgene zygosity in mice using an allele-specific method

Life Science Alliance, 2023
A novel, precise, rapid, and generalizable method to determine transgene zygosity in mice by allele-specific restriction enzyme digestion of PCR products from transgenes or homologous endogenous genes.
Jianqi Yang, Alison N DeVore, Daniel A Fu, Mackenzie M Spicer, Mengcheng Guo, Samantha G Thompson, Katelin E Ahlers-Dannen, Federica Polato, Andre Nussenzweig, Rory A Fisher   +9 more
doaj   +1 more source

Association Between Human Leukocyte Antigen Class I and II Diversity and Non-virus-associated Solid Tumors

Frontiers in Genetics, 2021
Homozygosity at human leukocyte antigen (HLA) loci might lead to reduced immunosurveillance and increased disease risk, including cancers caused by infection or of hematopoietic origin.
Zhiwei Liu, Allan Hildesheim
doaj   +1 more source

Pre-eclampsia (PE) and Chorionicity in Women with Twin Gestations [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Pre-Eclampsia (PE) affects 6-31% of pregnant women with multiple gestations. There are conflicting reports on the association of PE with Chorionicity and zygosity; however, there is a lack of information on this potential association in a ...
Anupama Singh, Arati Singh, Tarakeswari Surapaneni, Praveen Kumar Nirmalan   +3 more
doaj   +1 more source

The Differences in the dentition pattern in monozygotic twins based on panoramic examinations – case report on two pairs of twins

Journal of Education, Health and Sport, 2023
The aim of the study is to present two examples of twins with differences in their dentition revealed with the use of panoramic examinations. The analysis based on panoramic X-rays shows that even though the monozygotic twins share 100% of the genome ...
Weronika Miazek, Kamila Smala, Magdalena Piskórz, Ingrid Różyło-Kalinowska, Karolina Futyma-Gąbka   +4 more
doaj   +1 more source

Estimating heritability of height without zygosity information for twins under five years in low- and middle-income countries: An application of normal finite mixture distribution models

SSM: Population Health, 2022
Twin studies are widely used to estimate heritability of traits and typically rely on knowing the zygosity of twin pairs in order to determine variation attributable to genetics. Most twin studies are conducted in high resource settings.
Omar Karlsson, Benjamin W. Domingue, Rockli Kim, S.V. Subramanian   +3 more
doaj   +1 more source

Twinning rates in Chennai, India – A cross-sectional study

Journal of Family Medicine and Primary Care, 2022
Context: The city of Chennai is one of the largest metropolitan cities in India where apart from a large traditional population, there has been a continuous migration from rural areas and growing sophistication in lifestyle.
Anuradha J Kuppan, Victor Samuel, R Mahesh, P M Jaganath, Sukumaran Anil   +4 more
doaj   +1 more source