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Hydrogenosomes and Symbiosis

  • Chapter
Molecular Basis of Symbiosis

Part of the book series: Progress in Molecular and Subcellular Biology ((PMSB,volume 41))

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6 Conclusions

Hydrogenosomes are not the same. They evolved several times — independently — from mitochondria or the common ancestor of hydrogenosomes and mitochondria. This process, in general, involved the loss of the organellar genome together with the mitochondrial electron transport chain, and metabolic adaptations to anoxic environments such as the use of protons as terminal electron acceptors. Substantial differences in the physiological capacities of the various hydrogenosomes reflect their independent evolution through evolutionary tinkering. Notably, even the common denominator of these organelles, i.e., the production of hydrogen, can become marginal in certain hydrogenosomes.

The hydrogenosomal metabolism is crucial for the establishment of symbiotic associations, and sometimes differences in the host’s metabolism seem to be able to provide the clues for an understanding of the presence or absence of pears to be insufficient to explain the observations. Obviously, intrinsic properties of the various hosts and their symbionts play an important role, which are, at the moment, clearly not even beyond the level of a preliminary phenomenological description. Intensive efforts are required to analyse the elusive molecular basis of symbiotic associations. Many fascinating insights into the secrets of symbiotic associations await their discovery.

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Authors and Affiliations

  1. Department of Evolutionary Microbiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1, NL 6525 ED, Nijmegen, The Netherlands

    Johannes H. P. Hackstein

  2. Haskins Laboratories and Department of Chemistry and Physical Sciences, Pace University, New York, USA

    Nigel Yarlett

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  1. Johannes H. P. Hackstein
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  1. Section of Microbiology, Department of Biology, Maria-Ward-Str. 1a, 80638, Munich, Germany

    Jörg Overmann

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Hackstein, J.H.P., Yarlett, N. (2005). Hydrogenosomes and Symbiosis. In: Overmann, J. (eds) Molecular Basis of Symbiosis. Progress in Molecular and Subcellular Biology, vol 41. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28221-1_7

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