Virion
Morphology: |
Icosahedral |
Envelope: |
Yes |
Diameter (nm): |
60–125 |
Length (nm): |
– |
Structural components: |
Core, capsid, envelope |
Buoyant density (g/mL): |
1.15–1.18 |
Buoyant density method: |
– |
Lipid composition: |
– |
Additional information: |
Viral envelope proteins complexed with cellular lipid bilayer |
Genome
Nucleic acid: |
RNA |
|
Strandedness: |
Single-stranded |
|
Polarity: |
Positive-sense |
|
Configuration: |
Linear |
|
Segment organization: |
Segment no. 1 (kb): |
8.4–9.0 |
One segment(s): |
8.4–9 (kb) total (calculated) |
|
G + C content (%): |
53.1–54.2 |
|
mRNA transcripts: |
8–9 |
|
Open reading frames: |
10 |
|
Additional information: |
Viral particle contains 70 S RNA, i.e., two copies of 38 S polyadenylated RNA |
Replication
Entry mechanism: |
Receptors Glut-1 and Neuropilin-1 (for HTLV); viral envelope-mediated cell fusion |
Site of transcription: |
Nucleus |
Transcriptase: |
Cellular DNA-dependent RNA polymerase |
Site of genome replication: |
Integration into cellular chromosomal DNA |
Replicase: |
Virus-encoded RNA-dependent DNA polymerase |
Replication... |
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References
Araújo A, Lima MA, Silva MT (2008) Curr Treat Options Neurol 10:193–200
Coffin J, Hughes S, Varmus H (1997) Retroviruses. Cold Spring Harbor Laboratory Press, Cold Spring Harbor
Gillet N et al (2007) Retrovirology 4:18
Matsuoka M, Jeang KT (2007) Nat Rev Cancer 7:270–280
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Willems, L., Boxus, M., Florins, A., Bouzar, A. (2011). Deltaretrovirus. In: Tidona, C., Darai, G. (eds) The Springer Index of Viruses. Springer, New York, NY. https://doi.org/10.1007/978-0-387-95919-1_273
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DOI: https://doi.org/10.1007/978-0-387-95919-1_273
Publisher Name: Springer, New York, NY
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