Abstract
Any patient suspected of having a disorder of blood coagulation, either from family history or repeated bleeding episodes occurring spontaneously or secondary to trauma, should undergo appropriate diagnostic testing prior to the onset of pregnancy. The levels of the majority of coagulation factors increase during pregnancy, making accurate diagnosis of hereditary disorders of blood coagulation more difficult after the first trimester of pregnancy. Accurate diagnosis is based on clinical history, physical examination, and laboratory results. Abnormal bleeding or bruising following injury, dental extraction, or surgery is characteristic of disorders of blood coagulation. Additionally, a history of prolonged epistaxis, spontaneous bruising of the palms, hematomas, or bruises at the site of injection or immunization is suggestive of a hemostatic disorder.1–4
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© 1985 Plenum Publishing Corporation
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Eden, R.D. (1985). Disorders of Blood Coagulation Factors. In: Gleicher, N. (eds) Principles of Medical Therapy in Pregnancy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2415-7_186
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DOI: https://doi.org/10.1007/978-1-4613-2415-7_186
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9471-9
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