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Hypoxanthine Transport in Human Erythrocytes

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Purine Metabolism in Man—III

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 122B))

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Abstract

De novo synthesis of purines does not appear to take place in mature human erythrocytes because the enzymes for the pathway are absent1. Therefore purine bases should be normally have to be supplied exogenously to erythrocytes.

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References

  1. G.L. Brewer, General red cell metabolism, in “The red blood cell,” D. MacN. Surgeror, ed., Academic Press, New York (1974).

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  2. U.V. Lassen, Hypoxanthine transport in human erythrocytes, Biochim. Biophys. Acta 135: 146 (1967).

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  3. W. Gutensohn, Hypoxanthine phosphoribosyltransferase and hypoxanthine uptake in human erythrocytes, Hoppe-Seyler’s Z. Physiol. Chem. 356: 1105 (1975).

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  4. A. Hershko, A. Razin and J. Mager, Regulation of the synthesis of 5-phosphoribosyl-1-pyrophospnate in intact red blood cells and in cell-free preparations, Biochim. Biophys. Acta 184: 64 (1969)

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  5. E. Gerlach, R.H. Dreisbach, and B. Deuticke, Paper chromatographic separation of nucleotides, nucleosides, purines and pyrimi-dines, J. Chromatog. 18: 81 (1965).

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  6. A. Hershko, A. Razin, T. Shoshani, and J. Mager, Turnover of purine nucleotides in rabbit erythrocytes — studies in vitro, Biochim. Biophys. Acta 149: 59 (1967).

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  7. A. Giacomello and C. Salerno, Role of human hypoxanthine guanine phosphoribosyltransferase in nucleotide interconversion, These Proceedings.

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© 1980 Plenum Press, New York

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Salerno, C., Giacomello, A. (1980). Hypoxanthine Transport in Human Erythrocytes. In: Rapado, A., Watts, R.W.E., De Bruyn, C.H.M.M. (eds) Purine Metabolism in Man—III. Advances in Experimental Medicine and Biology, vol 122B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8559-2_13

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  • DOI: https://doi.org/10.1007/978-1-4684-8559-2_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8561-5

  • Online ISBN: 978-1-4684-8559-2

  • eBook Packages: Springer Book Archive

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