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Cytogenetic Resources and Information

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Cancer Cytogenetics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1541))

Abstract

The main databases devoted stricto sensu to cancer cytogenetics are the “Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer” (http://cgap.nci.nih.gov/Chromosomes/Mitelman), the “Atlas of Genetics and Cytogenetics in Oncology and Haematology” (http://atlasgeneticsoncology.org), and COSMIC (http://cancer.sanger.ac.uk/cosmic).

However, being a complex multistep process, cancer cytogenetics are broadened to “cytogenomics,” with complementary resources on: general databases (nucleic acid and protein sequences databases; cartography browsers: GenBank, RefSeq, UCSC, Ensembl, UniProtKB, and Entrez Gene), cancer genomic portals associated with recent international integrated programs, such as TCGA or ICGC, other fusion genes databases, array CGH databases, copy number variation databases, and mutation databases. Other resources such as the International System for Human Cytogenomic Nomenclature (ISCN), the International Classification of Diseases for Oncology (ICD-O), and the Human Gene Nomenclature Database (HGNC) allow a common language.

Data within the scientific/medical community should be freely available. However, most of the institutional stakeholders are now gradually disengaging, and well-known databases are forced to beg or to disappear (which may happen!)

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Author information

Authors and Affiliations

  1. Haematological Cancer Genetics & Stem Cell Genetics, Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK

    Etienne De Braekeleer

  2. Medical Genetics, Department of Medical Information, University Hospital, 86021, Poitiers, France

    Jean-Loup Huret

  3. Laboratoire CERBA, 95310, Saint Ouen l’Aumone, France

    Hossain Mossafa

  4. UMR 1170 INSERM, Gustave Roussy, 114 rue Edouard Vaillant, 94805, Villejuif, France

    Philippe Dessen

Authors
  1. Etienne De Braekeleer
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  2. Jean-Loup Huret
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  3. Hossain Mossafa
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  4. Philippe Dessen
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Corresponding authors

Correspondence to Jean-Loup Huret or Philippe Dessen .

Editor information

Editors and Affiliations

  1. Haematology Division Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong Prince of Wales Hospital, Shatin, Hong Kong, China

    Thomas S.K. Wan

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De Braekeleer, E., Huret, JL., Mossafa, H., Dessen, P. (2017). Cytogenetic Resources and Information. In: Wan, T. (eds) Cancer Cytogenetics. Methods in Molecular Biology, vol 1541. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6703-2_25

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  • DOI: https://doi.org/10.1007/978-1-4939-6703-2_25

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6701-8

  • Online ISBN: 978-1-4939-6703-2

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