Abstract
Paragangliomas are neuroendocrine neoplasms which can arise in multiple locations throughout the body, including the adrenal gland, head and neck region, respiratory tract, genitourinary system, mediastinum, and rarely the central nervous system. The vast majority of paragangliomas involving the central nervous system arise in the intradural space of the spinal cord and in the filum terminale region (1–5). Less frequently, paragangliomas have been described involving the intracranial region, sellar, and suprasellar locations (6–8). Most patients with paragangliomas present in the fourth to sixth decades of life with signs and symptoms related to lower back pain, motor and sensory deficits, or urinary and/or fecal incontinence (1,2). Radiographically, paragangliomas appear somewhat discrete, with areas of contrast enhancement (9). Tumors grossly are often well-circumscribed and frequently encapsulated.
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References
Sonneland, P.R., Scheithauer, B.W., LeChago, J., Crawford, B.G., Onofrio, B. (1986) Paraganglioma of the cauda equine region: clinicopathologic study of 31 cases with special reference to immunocytology and ultrastructure. Cancer 58: 1720–1735.
Moran, C.A., Rush, W., Mena, H. (1997) Primary spinal paragangliomas: a clinicopathological and immunohistochemical study of 30 cases. Histopathology 31: 167–173.
Horoupian, D.S., Kerson, L.A., Saintz, H., Valsamis, M. (1974) Paraganglioma of cauda equina. Cancer 33: 1337–1348.
Binkley, W., Vakili, S.T., Worth, R. (1982) Paraganglioma of the cauda equina. J. Neurosurg. 56: 275–279.
Ironside, J.W., Royds, J.A., Taylor, C.B., Timperley, W.R. (1985) Paraganglioma of the cauda equina: a histological, ultrastructural and immunohistochemical study of two cases with a review of the literature. J. Pathol. 145: 195–201.
Lamer, J.M., Hahn, S.S., Spaulding, C.A., Constable, W.C. (1992) Glomus jugulare tumors: long term control with radiation therapy. Cancer 69: 1813–1817.
Moffat, D.A., Hardy, D.G. (1989) Surgical management of large glomus jugulare tumours: infra-and trans-temporal approach. J. Laryngol. Otol. 103: 1167–1180.
Flint, E.W., Classen, D., Pang, D., Hirsch, W.L. (1993) Intrasellar and suprasellar paraganglioma: CT and MR findings. Am. J. Neuroradiol. 14: 1191–1193.
Aggarwal, S., Deck J.H.N., Kucharczyk W. (1993) Neuroendocrine tumor (paraganglioma) of the cauda equina: MR and pathologic findings. Am. J. Neuroradiol. 14: 1003–1007.
Djindjian, M., Ayache, P., Brugieres, S.P., Malapert, D., Baudrimont, M., Poirier, J. (1990) Giant gangliocytic paragangliorna of the filum terminale. J. Neurosurg. 73: 459–461.
Gaffney, E.F., Doorly, T., Dinn, J.J. (1986) Aggressive oncocytic neuroendocrine tumour (oncocytic paraganglioma) of the cauda equina. Histopathology 10: 311–319.
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© 2000 Springer Science+Business Media New York
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Prayson, R.A., Cohen, M.L. (2000). Paraganglioma. In: Practical Differential Diagnosis in Surgical Neuropathology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-037-7_29
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DOI: https://doi.org/10.1007/978-1-59259-037-7_29
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-61737-201-8
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